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中华结直肠疾病电子杂志 ›› 2016, Vol. 05 ›› Issue (02) : 110 -113. doi: 10.3877/cma.j.issn.2095-3224.2016.02.01

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体液检测在结直肠癌中应用的研究进展
邢宝才1,(), 刘伟1   
  1. 1. 100142 北京大学肿瘤医院暨北京市肿瘤防治研究所肝胆胰外一科,恶性肿瘤发病机制及转化研究教育部重点实验室
  • 收稿日期:2016-03-26 出版日期:2016-04-25
  • 通信作者: 邢宝才
  • 基金资助:
    国家自然科学基金(81371868)

The advances of the liquid biopsy in colorectal cancer

Baocai Xing1,(), Wei Liu1   

  1. 1. Department of Hepatopancreatobiliary Surgery, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing 100142, China
  • Received:2016-03-26 Published:2016-04-25
  • Corresponding author: Baocai Xing
  • About author:
    Corresponding author: Xing Baocai, Email:
引用本文:

邢宝才, 刘伟. 体液检测在结直肠癌中应用的研究进展[J/OL]. 中华结直肠疾病电子杂志, 2016, 05(02): 110-113.

Baocai Xing, Wei Liu. The advances of the liquid biopsy in colorectal cancer[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 05(02): 110-113.

体液检测是指以血液为主的体液标本中细胞及核酸的检测,包括了循环肿瘤细胞和循环肿瘤DNA两大类。能帮助实时动态监测肿瘤原发灶及转移复发灶基因组信息,协助早期诊断、疗效监测、预后判断,也有助于靶向治疗适应症的评估,从而推进精准医疗的实施。液态活检属于新型的无创性分子病理检测方式。在结直肠癌诊疗领域具有广阔的临床应用前景,也是推动肿瘤基础研究进展的重要助力。

Liquid biopsy refers to the analyses of circulating tumor cells or circulating tumor DNA that mainly exist in the bloodstream and other body fluid. Liquid biopsy is a novel kind of non-invasive technique and has a wide prospect of clinical application in the molecular pathological field. This review presents the advances of liquid biopsy and its clinical application values in the field of colorectal cancer, including prognosis assessment, early cancer screening and prediction of treatment responses.

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