探讨国产非放大高清晰度分光染色（CBI）内镜应用NICE分型对结直肠息肉及早癌诊治的准确性，并为临床诊疗工作提供借鉴。

选取2015年12月至2017年10月行结肠镜检查发现结直肠息肉样病变的患者96例，应用非放大或放大CBI内镜对病变进行内镜下实时分型，并行相应治疗或取病理，最终与病理结果相对照，进行比较分析。

非放大CBI内镜应用NICE分型诊断肿瘤性病变的准确性、特异性、敏感性、阳性及阴性预测值分别为95.2%、72.73%、100%、94.4%、100%，2型和3型的病变与其对应的病理诊断进行一致性分析，kappa值为0.795（≥0.75），说明具有理想的一致性，且一致性有统计学意义（P<0.01）。NICE分型与Sano分型对结直肠良性肿瘤性息肉和m-sm1癌与sm2-3癌相鉴别的一致性分析得到，kappa值为0.795，说明具有理想的一致性，且一致性有统计学意义（P<0.01）。

国产非放大CBI内镜应用NICE对结直肠息肉及早癌的诊治有良好的准确性，有助于结直肠息肉及早癌的鉴别诊断，避免不必要的治疗，节省医疗资源。

To investigate the accuracy of non magnifying high resolution Compound Band Imaging (CBI) endoscopy and NICE classification in the diagnosis and treatment of colorectal polyps and early cancer, and to provide reference for clinical diagnosis and treatment.

To select a total of 96 patients who underwent colonoscopy between December 2015 and October 2017 and who had colorectal polypoid lesions. The lesions were real-time classified with non magnifying or magnifying CBI endoscopy. And they were given the corresponding treatment or biopsy. Finally, the classifications were compared with the pathological findings. And the relationship of them was analyzed.

The accuracy, specificity, sensitivity, positive and negative predictive value of non magnifying CBI endoscopy for NICE classification of tumor lesions were 95.2%, 72.73%, 100%, 94.4%, 100%, respectively. Consistency of corresponding pathologic diagnosis of type 2 and type 3 lesions was analyzed. And the kappa value is 0.795 (more than 0.75), indicating the satisfactory consistency. And the consistency was statistically significant (P<0.01). The consistency between NICE classification and Sano classification which can differentiate colorectal benign tumor polyp and m-sm1 carcinoma and sm2-3 carcinoma was analyzed. And the kappa value is 0.795 (more than 0.75), indicating the satisfactory consistency. And the consistency was statistically significant (P<0.01).

The application of domestic non magnifying CBI endoscopy with NICE classification in the diagnosis and treatment of colorectal polyps with early cancer in China is of good accuracy, which is helpful for the differential diagnosis of colorectal polyps at early stage of cancer, avoiding unnecessary treatment and saving medical resources.