肝脏是结直肠癌转移的最常见部位，肝转移也是结直肠癌患者最主要死亡原因，很多研究证实经过多学科治疗可将部分初始不可切除或潜在可切除肝转移灶转化为可切除。本病例是多学科诊疗团队对初始不可切除肠癌肝转移患者实施的个体化综合治疗较成功的案例，患者是一个乙状结肠癌侵犯膀胱伴同时性肝多发转移的病例，肝转移灶为初始不可切除，通过全身化疗及适时恰当的多学科综合治疗，实现对肝转移瘤的彻底切除（R0切除），本文就此例患者诊疗过程中的一些经验和体会与大家一起来分享。

Liver metastasis is the most common metastasize site of colorectal cancer (CRC), liver metastasis is also the main cause of death in patients with CRC. Many studies have confirmed that multidisciplinary treatment of liver metastases could be turning some patients with initially unresectable or potentially resectable liver metastases into resectable. This case was successful case of multidisciplinary team (MDT) took individualized comprehensive treatment on patient with primary unresectable liver metastases from CRC. The patient was diagnosed with sigmoid colon carcinoma with invading the bladder and simultaneous multiple liver metastases and liver metastases were initial unresectable. Through systemic chemotherapy plus local timely and appropriate multidisciplinary comprehensive treatment, complete resection of liver metastases (R0 resection) was achieved. In this case report, we will report its treatment process and share some experience.