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中华结直肠疾病电子杂志 ›› 2017, Vol. 06 ›› Issue (05) : 402 -406. doi: 10.3877/cma.j.issn.2095-3224.2017.05.010

所属专题: 经典病例 文献

论著

909例新疆维吾尔族结直肠腺瘤及结直肠早癌相关危险因素分析
苏莎莎1, 孔文洁1, 赫晓磊1, 李紫琼1, 米热.阿依1, 高峰1,()   
  1. 1. 830000 新疆维吾尔自治区人民医院消化科
  • 收稿日期:2017-04-22 出版日期:2017-10-25
  • 通信作者: 高峰

The analysis of the risk factors in Uygur in Xinjiang area of the colorectal adenomatous polyosis progressing into the early colorectal cancer

Shasha Su1, Wenjie Kong1, Xiaolei He1, Ziqiong Li1, Ayi Mi Re.1, Feng Gao1,()   

  1. 1. Department of Gastroenterology, Xinjiang Uyger Muncipal People′Hospital, Urumchi Xinjiang 830000, China
  • Received:2017-04-22 Published:2017-10-25
  • Corresponding author: Feng Gao
  • About author:
    Corresponding author: Gao Fen, Email:
引用本文:

苏莎莎, 孔文洁, 赫晓磊, 李紫琼, 米热.阿依, 高峰. 909例新疆维吾尔族结直肠腺瘤及结直肠早癌相关危险因素分析[J/OL]. 中华结直肠疾病电子杂志, 2017, 06(05): 402-406.

Shasha Su, Wenjie Kong, Xiaolei He, Ziqiong Li, Ayi Mi Re., Feng Gao. The analysis of the risk factors in Uygur in Xinjiang area of the colorectal adenomatous polyosis progressing into the early colorectal cancer[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2017, 06(05): 402-406.

目的

探讨新疆维吾尔族结直肠腺瘤患者发生早期结直肠癌的危险因素。

方法

对新疆维吾尔自治区人民医院消化内镜中心2015年1月至2016年12月经结肠镜检查发现并经病理证实的909例早期结直肠癌及结直肠腺瘤病患者进行回顾性研究及现况调查,分析其临床特征,探讨新疆维吾尔族结直肠腺瘤患者进展为早期结肠癌的危险因素。

结果

早癌组中年龄、二级及三级亲属以内患结肠癌者、既往胆囊切除史、吸烟史均高于腺瘤组,差异有统计学意义(t=3.139,Χ2=4.439、10.497、4.479、7.842,P均<0.05)。在饮食习惯的调查中,两组谷物摄入量差异有统计学意义(Χ2=13.639,P<0.05),早癌组患者进食腌制食物每2~3天1次者多于腺瘤组。蔬菜摄入频率、水果摄入频率、腌制食物进食频率差异没有统计学意义(Χ2=1.711、6.579、10.461,P均>0.05)。Logistic回归分析发现,年龄≥60岁、三级以内家属恶性肿瘤史、胆囊切除术、吸烟史是结直肠腺瘤癌变为早期结直肠癌的危险因素(OR=2.420,5.632,7.623,5.234,P<0.05)。

结论

维吾尔族人群中年龄、三级以内亲属、胆囊切除术、吸烟史、是结直肠腺瘤进展为早期结直肠癌的危险因素。

Objective

To investigate the risk of the colorectal adenomatous polyosis progressing into the early colorectal cancer.

Methods

909 cases of colorectal adenomatous polyosis and early colorectal cancer confirmed by pathology were selected form January 2015 to December 2016, to explore the risk of the colorectal adenomatous polyosis progressing into the early colorectal cancer.

Results

There was marked diefference in age, secondary and tertiary relatives within the family history of colon cancer, smoking history, gallbladder excision history between the colorectal adenomatous polyosis and the early colorectal cancer (t=3.139, Χ2=4.439, 10.497, 4.479, 7.842, P<0.05). In the survey of dietary habits, there wasno marked diefference in the frequency of vegetable intake, the frequency of fruit intake, and the frequency of the pickled food between two groups (Χ2=1.711、6.579、10.461, P>0.05), but there was statistically differences in the frequency of grains intake and the patients of the early colorectal cancer eatting the pickled food (2~3 times Per day) were more than the patients of colorectal adenomatous polyosis (Χ2=13.639, P<0.05). In the Logistic regression analysis, the age, tertiary relatives within the family history of colon cancer, smoking history, gallbladder excision history maight be the risk of the colorectal adenomatous polyosis becoming into the early colorectal cancer (OR=2.420, 5.632, 7.623, 5.234, P<0.05).

Conclusion

The age, tertiary relatives within the family history of colon cancer, smoking history, gallbladder excision history maight be the risk of the colorectal adenomatous polyosis becoming into the early colorectal cancer.

表1 两组危险因素比较
表2 两组饮食相关因素比较[例(%)]
表3 多因素Logistic回归分析
表4 两组结肠镜下病变比较[例(%)]
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