| [1] |
Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2024, 74(3): 229-263.
|
| [2] |
Yamamoto H, Zhang S, Mizushima N. Autophagy genes in biology and disease[J]. Nat Rev Genet, 2023, 24(6): 382-400.
|
| [3] |
Zhang T, Yu J, Cheng S, et al. Research progress on the anticancer molecular mechanism of targets regulating cell autophagy[J]. Pharmacology, 2023, 108(3): 224-237.
|
| [4] |
Jain V, Singh MP, Amaravadi RK. Recent advances in targeting autophagy in cancer[J]. Trends Pharmacol Sci, 2023, 44(5): 290-302.
|
| [5] |
Liu S, Yao S, Yang H, et al. Autophagy: regulator of cell death[J]. Cell Death Dis, 2023, 14(10): 648.
|
| [6] |
Yamamoto H, Matsui T. Molecular mechanisms of macroautophagy, microautophagy, and chaperone-mediated autophagy[J]. J Nippon Med Sch, 2024, 91(1): 2-9.
|
| [7] |
Wang L, Klionsky DJ, Shen HM. The emerging mechanisms and functions of microautophagy[J]. Nat Rev Mol Cell Biol, 2022, 24(3): 186-203.
|
| [8] |
Wang Y, Liu J, Wang H, et al. Multiple regulatory mechanisms, functions and therapeutic potential of chaperone-mediated autophagy[J]. Theranostics, 2025, 15(7): 2778-2793.
|
| [9] |
Cao W, Li J, Yang K, et al. An overview of autophagy: mechanism, regulation and research progress[J]. Bull Cancer, 2021, 108(3): 304-322.
|
| [10] |
Li Q, Geng S, Luo H, et al. Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy[J]. Signal Transduct Target Ther, 2024, 9(1): 266.
|
| [11] |
Zhang Y, Li H, Lv L, et al. Autophagy: dual roles and perspective for clinical treatment of colorectal cancer[J]. Biochimie, 2023, 206: 49-60.
|
| [12] |
Garavaglia B, Vallino L, Ferraresi A, et al. Butyrate inhibits colorectal cancer cell proliferation through autophagy degradation of β-Catenin regardless of APC and β-Catenin mutational status[J]. Biomedicines, 2022, 10(5): 1131.
|
| [13] |
Zhao H, Ming T, Tang S, et al. Wnt signaling in colorectal cancer: pathogenic role and therapeutic target[J]. Molecular Cancer, 2022, 21(1): 144.
|
| [14] |
Debnath J, Gammoh N, Ryan KM. Autophagy and autophagy-related pathways in cancer[J]. Nat Rev Mol Cell Biol, 2023, 24(8): 560-575.
|
| [15] |
Li XL, Zhou J, Chen ZR, et al. P53 mutations in colorectal cancer - molecular pathogenesis and pharmacological reactivation[J]. World J Gastroenterol, 2015, 21(1): 84-93.
|
| [16] |
Tang J, Li Y, Xia S, et al. Sequestosome 1/p62: a multitasker in the regulation of malignant tumor aggression (Review)[J]. Int J Oncol, 2021, 59(4): 77.
|
| [17] |
Wang L, Wang Y, Lu Y, et al. Heterozygous deletion of ATG5 in Apc Min/+mice promotes intestinal adenoma growth and enhances the antitumor efficacy of interferon-gamma[J]. Cancer Biology & Therapy, 2015, 16(3): 383-391.
|
| [18] |
Li L, Jing L, Wang J, et al. Autophagic flux is essential for the downregulation of D-dopachrome tautomerase by atractylenolide I to ameliorate intestinal adenoma formation[J]. J Cell Commun Signal, 2018, 12(4): 689-698.
|
| [19] |
Leiphrakpam PD, Are C. PI3K/Akt/mTOR signaling pathway as a target for colorectal cancer treatment[J]. Int J Mol Sci, 2024, 25(6): 3178.
|
| [20] |
Tan XP, He Y, Huang YN, et al. Lomerizine 2HCl inhibits cell proliferation and induces protective autophagy in colorectal cancer via the PI3K/Akt/mTOR signaling pathway[J]. MedComm (2020), 2021, 2(3): 453-466.
|
| [21] |
Li JK, Sun HT, Jiang XL, et al. Polyphyllin Ⅱ induces protective autophagy and apoptosis via inhibiting PI3K/AKT/mTOR and STAT3 signaling in colorectal cancer cells[J]. Int J Mol Sci, 2022, 23(19): 11890.
|
| [22] |
Li Y, Yan W, Qin Y, et al. The anthraquinone derivative C2 enhances oxaliplatin-induced cell death and triggers autophagy via the PI3K/AKT/mTOR pathway[J]. Int J Mol Sci, 2024, 25(12): 6468.
|
| [23] |
Wang S, Li H, Yuan M, et al. Role of AMPK in autophagy[J]. Frontiers in Physiology, 2022, 13: 1015500.
|
| [24] |
Yuan W, Fang W, Zhang R, et al. Therapeutic strategies targeting AMPK-dependent autophagy in cancer cells[J]. Biochim Biophys Acta Mol Cell Res, 2023, 1870(7): 119537.
|
| [25] |
Xiang X, Tian Y, Hu J, et al. Fangchinoline exerts anticancer effects on colorectal cancer by inducing autophagy via regulation AMPK/mTOR/ULK1 pathway[J]. Biochem Pharmacol, 2021, 186: 114475.
|
| [26] |
Yu H, Huang Y, Ge Y, et al. Selenite-induced ROS/AMPK/FoxO3a/GABARAPL-1 signaling pathway modulates autophagy that antagonize apoptosis in colorectal cancer cells[J]. Discov Oncol, 2021, 12(1): 35.
|
| [27] |
Athamneh K, Alneyadi A, Alsamri H, et al. Origanum majorana Essential oil triggers p38 MAPK-mediated protective autophagy, apoptosis, and caspase-dependent cleavage of P70S6K in colorectal cancer cells[J]. Biomolecules, 2020, 10(3): 412.
|
| [28] |
Han SH, Lee JH, Woo JS, et al. Platycodin D induces apoptosis via regulating MAPK pathway and promotes autophagy in colon cancer cell[J]. Biomed Pharmacother, 2024, 172: 116216.
|
| [29] |
Gamage CDB, Kim JH, Yang Y, et al. Libertellenone T, a novel compound isolated from endolichenic fungus, induces G2/M phase arrest, apoptosis, and autophagy by activating the ROS/JNK pathway in colorectal cancer cells[J]. Cancers (Basel), 2023, 15(2): 489.
|
| [30] |
Li T, Li T, Zhang H, et al. Maintenance of the expression of c-FLIPL by Hsp70 to resist licochalcone a-induced anti-colorectal cancer effect through ERK-mediated autophagy induction[J]. Front Biosci (Landmark Ed), 2023, 28(12): 325.
|
| [31] |
Manzoor S, Muhammad JS, Maghazachi AA, et al. Autophagy: a versatile player in the progression of colorectal cancer and drug resistance[J]. Front Oncol, 2022, 12: 924290.
|
| [32] |
Yamamoto K, Iwadate D, Naito E, et al. Autophagy as a critical driver of metabolic adaptation, therapeutic resistance, and immune evasion of cancer[J]. Curr Opin Biotechnol, 2023, 84: 103012.
|
| [33] |
Xing F, Liu N, Wang C, et al. Caffeic acid phenethyl ester promotes oxaliplatin sensitization in colon cancer by inhibiting autophagy[J]. Sci Rep, 2024, 14(1): 14624.
|
| [34] |
Feng Z, Zhang S, Han Q, et al. Liensinine sensitizes colorectal cancer cells to oxaliplatin by targeting HIF-1α to inhibit autophagy[J]. Phytomedicine, 2024, 129: 155647.
|
| [35] |
Yu K, Pu H, Zhang X, et al. CLMP increases 5-fluorouracil sensitivity in colorectal cancer through the inhibition of autophagy[J]. Tissue Cell, 2025, 93: 102771.
|
| [36] |
Tessmann JW, Rocha MR, Morgado-Díaz JA. Mechanisms of radioresistance and the underlying signaling pathways in colorectal cancer cells[J]. J Cell Biochem, 2023, 124(1): 31-45.
|
| [37] |
Chaaya C, Zgheib G, El Karak F. Pharmacotherapy developments in autophagy inhibitors for bladder cancer[J]. Expert Opin Pharmacother, 2023, 24(17): 1853-1860.
|
| [38] |
Yazal T, Bailleul J, Ruan Y, et al. Radiosensitizing pancreatic cancer via effective autophagy inhibition[J]. Mol Cancer Ther, 2022, 21(1): 79-88.
|
| [39] |
Jiang T, Chen X, Ren X, et al. Emerging role of autophagy in anti-tumor immunity: implications for the modulation of immunotherapy resistance[J]. Drug Resist Updat, 2021, 56: 100752.
|
| [40] |
Zhang W, Chen L, Liu J, et al. Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer[J]. J Exp Clin Cancer Res, 2024, 43(1): 114.
|
| [41] |
Yamamoto K, Venida A, Yano J, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-Ⅰ[J]. Nature, 2020, 581(7806): 100-105.
|