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中华结直肠疾病电子杂志 ›› 2021, Vol. 10 ›› Issue (06) : 648 -653. doi: 10.3877/cma.j.issn.2095-3224.2021.06.013

综述

结直肠癌患者术后生活质量评估方法应用现状
郑明宇1, 张骞1, 王贵玉1,()   
  1. 1. 150081 哈尔滨医科大学附属第二医院结直肠肿瘤外科
  • 收稿日期:2021-04-28 出版日期:2021-12-25
  • 通信作者: 王贵玉
  • 基金资助:
    黑龙江省应用技术研究与开发计划(GA19C003); 黑龙江省省属本科高校中央支持地方高校改革发展基金(2020GSP05)

Application of quality of life assessment methods for postoperative patients with colorectal cancer

Mingyu Zheng1, Qian Zhang1, Guiyu Wang1,()   

  1. 1. Department of Colorectal Cancer Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China
  • Received:2021-04-28 Published:2021-12-25
  • Corresponding author: Guiyu Wang
引用本文:

郑明宇, 张骞, 王贵玉. 结直肠癌患者术后生活质量评估方法应用现状[J]. 中华结直肠疾病电子杂志, 2021, 10(06): 648-653.

Mingyu Zheng, Qian Zhang, Guiyu Wang. Application of quality of life assessment methods for postoperative patients with colorectal cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2021, 10(06): 648-653.

生活质量是指不同文化和价值体系中的个体,对目标、期望以及所关心事情相关的生存状况的体验,这一概念已经成为肿瘤患者临床疗效评估方法中不可或缺的组成部分。选择正确的生活质量评估方法,对于完善手术治疗效果分析以及提高患者术后生活质量水平至关重要。本文对结直肠癌患者术后生活质量评估方法的应用现状进行综述,为临床医师在随访和科研工作中选择恰当的评估方法提供参考。

Quality of life refers to the experience of individuals in different cultures and value systems on the living conditions related to goals, expectations and concerns. This concept has become an indispensable part of clinical efficacy evaluation methods for cancer patients. It is very important to choose the right QOL assessment method for improving the analysis of surgery and improving the QOL of patients after surgery. In this paper, the application of QOL assessment methods for colorectal cancer patients after operation was reviewed to provide reference for clinicians to choose appropriate assessment methods in follow-up and researches.

表1 结直肠癌患者生活质量评估量表介绍
简称 中英文全称 量表类型 条目数量 维度数量 维度内容 特点
QLQ-C30 生活质量核心调查问卷(Quality of Life Questionaire-Core 30) 普适性-癌症 30 15 5个功能维度、9个症状维度和总体生活质量维度 信度较高,广泛应用于临床及科研
QLQ-CR38 结直肠癌特异性生活质量调查问卷38(Quality of Life Questionaire-Colorectal 38) 特异性-结直肠癌 38 12 4个功能维度、8个症状维度 内容全面,个体化检测能力较强,但协调性较差
QLQ-CR29 直肠癌特异性生活质量调查问卷29(Quality of Life Questionaire-Colorectal 29) 特异性-结直肠癌 29 17 6个基本维度、4个性相关维度和7个单独维度 内容简便且具有针对性,尤其对直肠癌敏感
FACT-C 结直肠癌治疗功能评价系统(Functional Assessment of Cancer Therapy Colorectal Cancer) 特异性-结直肠癌 36 5 躯体状况、社会/家庭状况、情感状况、功能状况和结直肠癌特异性条目 结直肠癌应用最为广泛
SF-36 健康状况调查简表(MOS item short from health survey) 通用性 36 8 躯体功能、躯体角色、疼痛、总体健康、活力、社会功能、角色情绪和心理健康 广泛应用于普通人群生活质量评估
CCF-CaQL 克利夫兰诊所结直肠癌生活质量调查问卷(The New Cleveland Clinic Colorectal Cancer Quality of Life Questionnaire) 特异性-结直肠癌 25 4 生活质量、肠道功能、疼痛和对未来的担忧 结合手术特有因素,对低位直肠癌患者术后长期生活质量评估有重要意义
FIQL 大便失禁生活质量量表(Fecal Incontinence Quality of Life scale) 特异性-结直肠癌 29 4 生活方式、竞争/行为、抑郁/自我认知、尴尬 将直肠癌和其他胃肠道疾病患者进行显著区分,维度稳定性高
FISI 大便失禁严重性指数(Fecal Incontinence Severity Index) 普适性-大便失禁症状 31 9 失禁影响、角色、身体功能、社会功能、个人功能、情绪问题、睡眠、精力和总体健康维度 国际通用评估大便失禁症状的严重程度和对生活质量影响的量表
FLIC 癌症患者生活功能指标(The Functional Living Index-Cancer) 普适性-癌症 22 5 生理适应与能力、情绪症状、社会生活能力、家庭状态、恶心呕吐 对角色认知、社交能力、情绪状态及主观感受等精准测评
GIQLI 胃肠生活质量量表(Gastrointestinal Quality of Life Index) 特异性-消化道疾病 36 4 自觉症状、躯体生理功能、生理情绪状况和日常功能 在受检患者中区分出看似正常的人群,但功能维度内容相对不足
NHP 诺丁汉健康调查问卷(Nottingham Health Profile) 普适性-癌症 38 6 精力、疼痛、情绪反应、睡眠、社会孤独感和身体活动能力 对单病种癌症患者生活质量结果具有可靠性,但对多元发癌症干扰因素敏感性较差
[1]
曹毛毛, 陈万青. GLOBOCAN 2020全球癌症统计数据解读[J].中国医学前沿杂志(电子版), 2021, 13(3): 63-69.
[2]
万德森. 结直肠癌流行病学与预防[J].中国中西医结合外科杂志, 2011, 17(1): 3-7.
[3]
Fiore JFJr, Figueiredo S, Balvardi S, et al. How do we value post-operative recovery?: A systematic review of the measurement properties of patient-reported outcomes after abdominal surgery[J]. Ann Surg, 2018, 267: 656-669.
[4]
McColl E, Meadows K, Barofsky I. Cognitive aspects of survey methodology and quality of life assessment[J].Qual Life Res, 2003, 12(3): 217-218.
[5]
Korolija D, Sauerland S, Wood-Dauphinée S, et al. Evaluation of quality of life after laparoscopic surgery: evidence-based guidelines of the European Association for Endoscopic Surgery[J].Surg Endosc, 2004, 18(6): 879-897.
[6]
Aaronson NK, Ahmedzai S, Bergman B, et al. The european organization for research and treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology[J]. J Natl Cancer Inst, 1993, 85(5): 365-376.
[7]
Whistance RN, Conroy T, Chie W, et al. Clinical and psychometric validation of the EORTC QLQ-CR29 questionnaire module to assess health-related quality of life in patients with colorectal cancer[J]. Eur J Cancer, 2009, 45(17): 3017-3026.
[8]
Kasper B. The EORTC QLQ-C30 summary score as a prognostic factor for survival of patients with cancer: A commentary[J]. Oncologist, 2020, 25(4): e610-e611.
[9]
Aaronson NK, Ahmedzai S, Bergman B, et al. The european organization for research and treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology[J]. J Natl Cancer Inst, 1993, 85(5): 365-376.
[10]
孟琼, 万崇华, 罗家洪. 癌症患者生活质量测定量表EORTC QLQ-C30的应用概况[J]. 国外医学(社会医学分册), 2004, (4): 147-150.
[11]
Kong D, Yang Z, Wang Y, et al. Development and validation of a simplified chinese version of EORTC QLQ-CR38 to measure the quality of life of patients with colorectal cancer[J].Oncology, 2012, 83(4): 201-209.
[12]
姜丹, 杨铮, 万崇华, 等. 大肠癌患者生命质量测定量表QLQ-CR68中文版的研制与应用评价[J].中国肿瘤, 2007, (11): 862-865.
[13]
黄明君, 韦诗友, 李智, 等. EORTC QLQ-CR38在结直肠癌术后患者中的应用现状[J].中国现代普通外科进展, 2015, 18(5): 383-387.
[14]
Rauch P, Miny J, Conroy T, et al. Quality of life among disease-free survivors of rectal cancer[J]. J Clin Oncol, 2004, 22(2): 354-360.
[15]
Arraras JI, Suárez J, Arias de la Vega F, et al. The EORTC quality of life questionnaire for patients with colorectal cancer: EORTC QLQ-CR29 validation study for Spanish patients[J]. Clin Transl Oncol, 2011, 13(1): 50-56.
[16]
张云凤, 林锦波, 郑宛冰, 等. EORTC QLQ-CR29在结直肠癌患者生活质量评价中的应用[J]. 广州医科大学学报, 2018, 46(2): 130-132.
[17]
van der Hout A, Neijenhuijs KI, Jansen F, et al. Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29[J].Support Care Cancer, 2019, 27(7): 2395-2412.
[18]
Cella DF, Tulsky DS, Gray G, et al. The functional assessment of cancer therapy scale: development and validation of the general measure[J]. J Clin Oncol, 1993, 11(3): 570-579.
[19]
Yu CL, Fielding R, Chan CL, et al. Measuring quality of life of Chinese cancer patients: A validation of the Chinese version of the functional assessment of cancer therapy-general (FACT-G) scale[J]. Cancer, 2000, 88(7): 1715-1727.
[20]
杨铮, 卢玉波, 李云峰, 等. 大肠癌患者生命质量测定量表FACT-C(V4.0)中文版应用评价[J]. 中国组织工程研究与临床康复, 2007, (43): 8753-8756.
[21]
Wan C, Zhang D, Yang Z, et al. Validation of the simplified Chinese version of the FACT-B for measuring quality of life for patients with breast cancer[J]. Breast Cancer Res Treat, 2007, 106(3): 413-418.
[22]
刘敏, 吴华章. 结直肠癌患者生命质量测定量表FACT-C中文版的有效性评价[J]. 中国病案, 2020, 21(3): 90-92.
[23]
Ward WL, Hahn EA, Mo F, et al. Reliability and validity of the functional assessment of cancer therapy-colorectal (FACT-C) quality of life instrument[J]. Qual Life Res, 1999, 8(3): 181-195.
[24]
Ganesh V, Agarwal A, Popovic M, et al. Comparison of the FACT-C, EORTC QLQ-CR38, and QLQ-CR29 quality of life questionnaires for patients with colorectal cancer: a literature review[J]. Support Care Cancer, 2016, 24(8): 3661-3668.
[25]
李鲁, 王红妹, 沈毅. SF-36健康调查量表中文版的研制及其性能测试[J]. 中华预防医学杂志, 2002, 36(2): 38-42.
[26]
Lins L, Carvalho FM. SF-36 total score as a single measure of health-related quality of life: scoping review[J].SAGE Open Med, 2016, 4: 2050312116671725.
[27]
Grande GE, Farquhar MC, Barclay SI, et al. Quality of life measures (EORTC QLQ-C30 and SF-36) as predictors of survival in palliative colorectal and lung cancer patients[J]. Palliat Support Care, 2009, 7(3): 289-297.
[28]
Zutshi M, Aiello A, Fuerst A, et al. Reducing patient burden and improving data quality with the new cleveland clinic colorectal cancer quality of life questionnaire[J]. Dis Colon Rectum, 2020, 63(4): 469-487.
[29]
Rockwood TH, Church JM, Fleshman JW, et al. Fecal incontinence quality of life scale: quality of life instrument for patients with fecal incontinence[J].Dis Colon Rectum, 2000, 43(1): 9-16; discussion 16-17.
[30]
't Hoen LA, Utomo E, Schouten WR, et al. The fecal incontinence quality of life scale (FIQL) and fecal incontinence severity index (FISI): validation of the dutch versions[J]. Neurourol Urodyn, 2017, 36(3): 710-715.
[31]
Kwon S, Visco AG, Fitzgerald MP , et al. Validity and reliability of the modified manchester health questionnaire in assessing patients with fecal incontinence[J]. Diseases of the Colon & Rectum, 2005, 48(2): 323-331; discussion 331-334.
[32]
Jelovsek JE, Chen Z, Markland AD, et al. Minimum important differences for scales assessing symptom severity and quality of life in patients with fecal incontinence[J]. Female Pelvic Med Reconstr Surg, 2014, 20(6): 342-348.
[33]
King MT, Dobson AJ, Harnett PR. A comparison of two quality-of-life questionnaires for cancer clinical trials: the functional living index--cancer (FLIC) and the quality of life questionnaire core module (QLQ-C30)[J]. J Clin Epidemiol, 1996, 49(1): 21-29.
[34]
Fong DY, Lee AH, Tung SY, et al. The functional living index-cancer is a reliable and valid instrument in Chinese cancer patients[J].Qual Life Res, 2014, 23(1): 311-316.
[35]
Cheung YB, Ng GY, Wong LC, et al. Measuring quality of life in Chinese cancer patients: a new version of the functional living index for cancer (Chinese)[J]. Ann Acad Med Singap, 2003, 32(3): 376-380.
[36]
Slim K, Bousquet J, Kwiatkowski F, et al. Première validation de la version française de l'index de qualité de vie pour les maladies digestives (GIQLI) [First validation of the French version of the Gastrointestinal Quality of Life Index (GIQLI)][J]. Gastroenterol Clin Biol, 1999, 23(1): 25-31.
[37]
Jenkinson C, Fitzpatrick R. Measurement of health status in patients with chronic illness: comparison of the Nottingham health profile and the general health questionnaire[J]. Fam Pract, 1990, 7(2): 121-124.
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