| 1 |
Bray F, Ferlay J, Soerjomataram L, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA: A Cancer Journal for Clinicians, 2018, 68(6): 394-424.
|
| 2 |
Zhu J, Tan Z, Hollis-Hansen K, et al. Epidemiological trends in colorectal cancer in China: an ecological Study[J]. Dig Dis, 2017, 62(1): 235-243.
|
| 3 |
Arnold M, Sierra MS, Laversanne M, et al. Global patterns and trends in colorectal cancer incidence and mortality[J]. Gut, 2017, 66(4): 683-691.
|
| 4 |
Ganesh K, Stadler K, Cercek A, et al. Immunotherapy in colorectal cancer: rationale, challenges and potential[J]. Nature Reviews Gastroenterology & Hepatology, 2019, 16(6): 361-375.
|
| 5 |
Boland P, Ma W. Immunotherapy for colorectal cancer[J]. Cancers, 2017, 9(5): 50.
|
| 6 |
Sato T, Vrise R, Snippert H, et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche[J]. Nature, 2009, 459(7244): 262-265.
|
| 7 |
Lancaster M, Knoblich J. Organogenesis in a dish: Modeling development and disease using organoid technologies[J]. Science, 2014, 345(6194): 1247125.
|
| 8 |
Hunh M, Dorrell C, Boj S, et al. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration[J]. Nature, 2013, 494(7436): 247-250.
|
| 9 |
Barker N, Huch M, Kujala P, et al. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro[J]. Cell Stem Cell, 2010, 6(1): 25-36.
|
| 10 |
Lancater M, Renner M, Martin C, et al. Cerebral organoids model human brain development and microcephaly[J]. Nature, 2013, 501(7467): 373-379.
|
| 11 |
Xia Y, Nivet E, Martinez L, et al. Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells[J]. Nat Cell Biol, 2013, 515(12): 1507-1515.
|
| 12 |
Nakano T, Ando S, Tkata N, et al. Self-formation of optic cups and storable stratified neural retina from human ESCs[J]. Cell Stem Cell, 2012, 10(6): 771-785.
|
| 13 |
Levy E, Delvin E, Menard D, et al. Functional development of human fetal gastrointestinal tract[J]. Methods Mol Biol, 2009, 550: 205-224.
|
| 14 |
Crespo M, Vilar E, Tsai S, et al. Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing[J]. Nat Med, 2017, 23(7): 878-884.
|
| 15 |
Barretina J, Caponigro G, Stransky N, et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensi- tivity[J]. Nature, 2012, 483(7391):603-607.
|
| 16 |
Jin K, Teng L, Shen Y, et al. Patient-derived human tumour tissue xenografts in immunodeficient mice: a systematic review[J]. Clin Transl Oncol, 2010, 12(7): 473-480.
|
| 17 |
Wetering M, Francies H, Francies J, et al. Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients[J]. Cell, 2015, 161(4): 933-945.
|
| 18 |
Fujii M, Shimokawa M, Date S, et al. A colorectal tumor organoid library demonstrates progressive loss of niche factor requirements during Tumorigenesis[J]. Cell Stem Cell, 2016, 18(6): 827-838.
|
| 19 |
Schutte M, Risch T, Azar N, et al. Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors[J]. Nat Commun, 2017, 8: 14262.
|
| 20 |
Vlachogiannis G, Hedayat S, al Vatsiouet A. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers[J]. Science, 2018, 359(6378): 920-926.
|
| 21 |
Ganesh K, Wu C, O'Rourke KP, et al. A rectal cancer organoid platform to study individual responses to chemoradiation[J]. Nature Medicine, 2019, 25(10):1607-1614.
|
| 22 |
Ooft S, Weeber F, Dijkstra K, et al. Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients[J]. Sci Transl Med, 2019, 11(513):eaay2574.
|
| 23 |
Yao Y, Xu X, Yang L, et al. Patient-derived organoids predict chemoradiation responses of locally advanced rectal cancer[J]. Cell Stem Cell, 2020, 26(1): 17-26.
|
| 24 |
Yan H, Siu H, Ho S, et al. Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles[J]. Cut, 2020, 0: 1-15.
|
| 25 |
Weeber F, Ooft S, Dijkstra J, et al. Tumor organoids as a pre-clinical cancer model for drug discovery[J]. Cell Chem Biol, 2017, 24(9): 1092-1100.
|
| 26 |
Narasimhan V, Wright J, Churchill M, et al. Medium-throughput drug screening of patient-derived organoids from colorectal peritoneal metastases to direct personalized therapy[J]. Clin Cancer Res, 2020, 26(14): 3662-3670.
|
| 27 |
Drost J, Jaarsveld R, Ponsioen B, et al. Sequential cancer mutations in cultured human intestinal stem cells[J]. Nature, 2015, 521(7550): 43-47.
|
| 28 |
Takeda H, Kataoka S, Nakayama M, et al. CRISPR-Cas9-mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes[J]. Proc Natl Acad Sci USA, 2019, 116(31):15635-15644.
|