结直肠同时性+异时性多原发四重癌一例报道并文献复习

doi:10.3877/cma.j.issn.2095-3224.2022.01.013

中华结直肠疾病电子杂志 ›› 2022, Vol. 11 ›› Issue (01) : 82 -85. doi: 10.3877/cma.j.issn.2095-3224.2022.01.013

病例报道

结直肠同时性+异时性多原发四重癌一例报道并文献复习

杨勇¹, 郑帆¹, 黄彬², 郑恢超², 田跃², 童卫东²^,^†(

)

^1. 618000　德阳市人民医院胃肠外科
^2. 400042　重庆，陆军军医大学陆军特色医学中心普通外科

收稿日期:2021-04-28 出版日期:2022-02-25
通信作者: 童卫东
基金资助:
陆军军医大学人才临床创新基金(2019CXLCB004)

Synchronous and metachronous multiple primary colorectal four-cancer: a case report and literature review

Yong Yang¹, Fan Zheng¹, Bin Huang², Huichao Zheng², Yue Tian², Weidong Tong²^,^†()

^1. Department of Gastrointestinal Surgery, People's Hospital of Deyang City, 618000 Deyang, China
^2. Department of General Surgery, Army Medical Center, Army Medical University, 400042 Chongqing, China

Received:2021-04-28 Published:2022-02-25
Corresponding author: Weidong Tong

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多原发结直肠癌（MPCC）又称重复性结直肠癌，在临床上的发病率呈逐年上升趋势，其发病原因及机制不详，目前尚无统一、规范的诊治指南，临床医师极易漏诊，延误病情。本文报道1例结直肠同时性+异时性多原发四重癌的病例并复习文献，旨在提高临床医师对MPCC诊治的警觉性。

关键词: 直肠肿瘤, 多原发结直肠癌, 同时性, 异时性, 结肠镜

Multiple primary colorectal cancer (MPCC), also known as repetitive colorectal cancer, has a increasing morbidity rate in recent years. However, the exact etiology and pathogenesis of MPCC are still unknown. Moreover, there is no standard guideline for clinicians, which may lead to missed diagnosis and delay treatment. In this study, we aim to improve the clinicial alertness of diagnosis and treatment of MPCC by describing a case diagnosed synchronous and metachronous multiple primary colorectal four-cancer. Some related articals are also reviewed.

Key words: Rectal neoplasms, Multiple primary colorectal cancer, Synchronous, Metachronous, Colonoscopy

图1 术前结肠镜检查

图2 术后大体标本

图3 术后病理图像。3A：（原吻合口）溃疡型黏液腺癌；3B：（乙状结肠）溃疡型中分化腺癌；3C：（直肠）溃疡型中分化腺癌

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