随着肿瘤治疗手段的不断改进，肿瘤患者生存时间明显延长，随之而来的第二原发肿瘤的发生率也在增加。双重癌因原发部位及生物学行为不同，治疗的方法和顺序也不尽相同，目前暂无标准治疗模式。本病例为结肠多原发癌合并甲状腺癌肺转移，通过多学科诊疗团队制定个体化治疗方案，在保证患者生活质量的前提下，延长了生存时间。现将该病例诊断和治疗过程中的体会与大家分享。

With the improvement of the cancer treatment strategy, the survival time of tumor patients has been significantly extended, followed by increased incidence of secondary primary tumor. There is no standard treatment strategy for multiple primary carcinomas due to different origination and biology. Here we reported a case of multiple primary colon carcinomas with thyroid carcinoma with lung metastases. Under the guidance of multidisciplinary team, individualized treatment strategy successfully yielded a better quality of life and longer survival time.