《肿瘤整合诊治技术指南·NOSES技术（结直肠癌部分）》由中国抗癌协会NOSES专业委员会和大肠癌专业委员会联合制定，系统阐述了结直肠癌经自然腔道取标本手术（NOSES）的术式命名、适应证与禁忌证、无菌与无瘤操作规范、消化道重建及并发症防治等内容。指南详细介绍了结直肠癌NOSES的10类21种NOSES术式，覆盖结直肠各部位肿瘤，并明确了不同术式的操作要点及适用条件。《指南》强调手术团队需具备丰富的腹腔镜经验，严格把握适应证，并规范无菌与无瘤技术，包括术前准备、术中操作技巧及术后管理。此外，指南还总结了吻合口漏、腹腔感染等主要并发症的预防与处理策略，为临床开展结直肠癌NOSES提供了重要参考。

The guideline for integrated diagnosis and treatment of cancer-NOSES technology (colorectal cancer section) was jointly developed by the NOSES Professional Committee and the Colorectal Cancer Professional Committee of the Chinese Anti-Cancer Association. It systematically elaborates on the nomenclature of NOSES procedures, indications and contraindications, aseptic and non-tumor surgical protocols, digestive tract reconstruction, and prevention and management of complications for natural orifice specimen extraction surgery (NOSES) in colorectal cancer. The guideline details 10 categories and 21 types of NOSES procedures, covering tumors in various segments of the colorectum, and clarifies the key technical points and applicable conditions for each procedure. The guideline emphasizes that surgical teams must possess extensive laparoscopic experience, strictly adhere to indications, and standardize aseptic and non-tumor techniques, including preoperative preparation, intraoperative skills, and postoperative management. Additionally, it summarizes strategies for preventing and managing major complications such as anastomotic leakage and intra-abdominal infections, providing critical references for the clinical application of NOSES in colorectal cancer.