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中华结直肠疾病电子杂志 ›› 2025, Vol. 14 ›› Issue (04) : 299 -306. doi: 10.3877/cma.j.issn.2095-3224.2025.04.002

指南与共识

结直肠癌术中放疗专家共识(2025版)
中国医师协会结直肠肿瘤专业委员会术中放疗协作组   
  • 收稿日期:2025-06-06 出版日期:2025-08-25

‌Expert consensus on intraoperative radiation therapy for colorectal cancer (2025 Edition)

Intraoperative Radiotherapy Working Group, Colorectal Cancer Professional Committee of the Chinese Medical Doctor Association   

  • Received:2025-06-06 Published:2025-08-25
引用本文:

中国医师协会结直肠肿瘤专业委员会术中放疗协作组. 结直肠癌术中放疗专家共识(2025版)[J/OL]. 中华结直肠疾病电子杂志, 2025, 14(04): 299-306.

Intraoperative Radiotherapy Working Group, Colorectal Cancer Professional Committee of the Chinese Medical Doctor Association. ‌Expert consensus on intraoperative radiation therapy for colorectal cancer (2025 Edition)[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2025, 14(04): 299-306.

中国结直肠癌的发病率和死亡率近年来呈持续上升趋势,已成为威胁国民健康的重大公共卫生问题。针对中晚期直肠癌患者,国内外权威指南推荐新辅助放疗作为标准治疗方案。术中放射治疗(IORT)作为近年来快速发展的治疗模式,通过与手术的精准配合,展现出靶区定位精确、局部控制优势显著、周围组织损伤风险低等技术特点。然而,其临床应用仍面临诸多挑战,包括适应证界定、技术操作规范、疗效评价体系及长期预后数据等关键问题亟待系统论证与循证支持。基于此背景,中国医师协会结直肠肿瘤专业委员会术中放疗协作组牵头,组织多学科权威专家,系统整合国内外最新研究证据与临床实践经验,共同编撰完成《结直肠癌术中放疗专家共识(2025版)》。本共识旨在为临床实践提供参考,并推动该领域规范化诊疗进程和高质量发展。

Colorectal cancer has exhibited a persistently rising incidence and mortality rate in China, emerging as a critical public health challenge. For patients with locally advanced rectal cancer, neoadjuvant radiotherapy remains the standard treatment recommended by domestic and international guidelines. Intraoperative radiation therapy (IORT), an modality integrating radiotherapy with surgical intervention, has gained prominence in recent years due to its precision in target localization, enhanced local control efficacy, and reduced risk of perioperative tissue damage. However, unresolved issues persist regarding standardized indications, technical implementation protocols, efficacy evaluation systems, and long-term outcome validation, necessitating evidence-based consensus and multicenter clinical research. To address these challenges,‌ Intraoperative Radiotherapy Working Group, Colorectal Cancer Professional Committee of the Chinese Medical Doctor Association convened multidisciplinary experts. Synthesizing global evidence and clinical experience, the group formulated the expert consensus on intraoperative radiation therapy for colorectal cancer (2025 Edition). This consensus aims to serve as a reference for clinical practice and to advance standardized diagnostic and therapeutic protocols, fostering high-quality development in this field.

图1 术中放疗应用方式
图2 术中放疗治疗结直肠癌的流程图
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