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中华结直肠疾病电子杂志 ›› 2025, Vol. 14 ›› Issue (02) : 174 -178. doi: 10.3877/cma.j.issn.2095-3224.2025.02.010

综述

肠道微生态在放射性肠炎及其治疗中的研究进展
肖洋洋1, 崔佳瞿2, 黄作喜1, 李坚1, 廖传文1,()   
  1. 1. 330006 南昌,江西省人民医院(南昌医学院第一附属医院)胃肠外科
    2. 200072 同济大学附属上海第十人民医院结直肠病专科 肠道微生态诊疗中心
  • 收稿日期:2024-11-15 出版日期:2025-04-25
  • 通信作者: 廖传文

Research progress of gut microbiota in radiation enteritis and its treatment

Yangyang Xiao1, Jiaqu Cui2, Zuoxi Huang1, Jian Li1, Chuanwen Liao1,()   

  1. 1. Department of Gastrointestinal Surgery,Jiangxi Provincial People's Hospital,The First Affiliated Hospital of Nanchang Medical College,Nanchang 330006,China
    2. Intestinal Microenvironment Treatment Center of General Surgery,Shanghai Tenth People's Hospital,Tongji University School of Medicine,Shanghai 200072,China
  • Received:2024-11-15 Published:2025-04-25
  • Corresponding author: Chuanwen Liao
引用本文:

肖洋洋, 崔佳瞿, 黄作喜, 李坚, 廖传文. 肠道微生态在放射性肠炎及其治疗中的研究进展[J/OL]. 中华结直肠疾病电子杂志, 2025, 14(02): 174-178.

Yangyang Xiao, Jiaqu Cui, Zuoxi Huang, Jian Li, Chuanwen Liao. Research progress of gut microbiota in radiation enteritis and its treatment[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2025, 14(02): 174-178.

放射性肠炎(RE)是指放射治疗盆腔、腹腔或腹膜后恶性肿瘤所引起的肠道并发症,是临床放射治疗中常见的并发症之一。肠道微生态与人类健康密切相关,许多研究支持肠道微生态在RE的发生和发展中起着关键作用,通过调节微生态平衡可达到预防和辅助治疗RE的目的。笔者着重综述肠道微生态与RE的关系及相关机制,同时探讨肠道微生态疗法在RE临床治疗中的应用。

Radiation enteritis (RE) refers to the intestinal complications caused by radiation therapy for malignant tumors in the pelvic,abdominal,or retroperitoneal regions,and is one of the common complications in clinical radiation therapy. The gut microbiota is closely related to human health,and many studies support the crucial role of gut microbiota in the occurrence and development of RE. By regulating the balance of microbiota,the goal of preventing and assisting in the treatment of RE can be achieved. The author focuses on summarizing the relationship and related mechanisms between gut microbiota and RE,and explores the application of gut microbiota therapy in the clinical treatment of RE.

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