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中华结直肠疾病电子杂志 ›› 2019, Vol. 08 ›› Issue (06) : 606 -609. doi: 10.3877/cma.j.issn.2095-3224.2019.06.011

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论著

一期全结肠直肠切除、回肠储袋肛管吻合术治疗溃疡性结肠炎的安全性及生活质量评估
夏霖1, 王自强1, 舒晔1,()   
  1. 1. 610041 成都,四川大学华西医院胃肠外科
  • 收稿日期:2018-04-27 出版日期:2019-12-25
  • 通信作者: 舒晔
  • 基金资助:
    四川省科技计划重点研发项目(No.2019YFS0261)

Safety and quality of life of one-stage total colorectal resection and ileal pouch anal anastomosis for ulcerative colitis

Lin Xia1, Ziqiang Wang1, Ye Shu1,()   

  1. 1. Department of Gastrointestinal Surgery, West China Hospital, Chengdu 610041, China
  • Received:2018-04-27 Published:2019-12-25
  • Corresponding author: Ye Shu
  • About author:
    Corresponding author: Shu Ye, Email:
引用本文:

夏霖, 王自强, 舒晔. 一期全结肠直肠切除、回肠储袋肛管吻合术治疗溃疡性结肠炎的安全性及生活质量评估[J/OL]. 中华结直肠疾病电子杂志, 2019, 08(06): 606-609.

Lin Xia, Ziqiang Wang, Ye Shu. Safety and quality of life of one-stage total colorectal resection and ileal pouch anal anastomosis for ulcerative colitis[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2019, 08(06): 606-609.

目的

探讨一期全结直肠切除、回肠储袋肛管吻合术(IPAA)治疗溃疡性结肠炎(UC)的安全性和术后生活质量。

方法

回顾性分析四川大学华西医院胃肠外科中心2014年1月至2015年12月行一期IPAA治疗的22例UC患者的术中和术后临床资料及生活质量评分,探讨该术式的技术要点、安全性及生活质量。

结果

22例患者均成功实施IPAA,共18例患者发生20例次并发症,其中,中-重度并发症(Clavien-Dindo Ⅲ~Ⅳ)2例次:1例发生胸腔积液行胸腔穿刺术,1例因术后肺部感染入ICU治疗,未发生储袋肛管吻合口漏。术后3月及12月时随访患者平均排便次数为(6.75±1.24)次/天和(4.18±1.00)次/天,克利夫兰总体生活质量评价(CGQL)为(0.85±0.08)及(0.92±0.06)。

结论

对择期UC患者,采用一期IPAA治疗安全可行,术后患者排便功能及生活质量满意。

Objective

To investigate the safety and postoperative quality of life for patients with ulcerative colitis (UC) treated with one-stage total colorectal resection and ileal pouch anal anastomosis (IPAA).

Methods

The clinical and postoperative clinical data and quality of life scores of 22 patients with UC who underwent IPAA treatment from January 2014 to December 2015 in the Gastrointestinal Surgery Center of West China Hospital of Sichuan University were retrospectively analyzed.

Results

All of the 22 patients were successfully enrolled and were treated with IPAA. A total of 18 patients had 20 complications/time, including 2 cases of moderate-to-severe complications (Clavien-Dindo III~IV), one case of thoracic puncture with pleural effusion, one patient was treated with ICU due to postoperative pulmonary infection. There was no anastomotic leakage of all the patients. The average number of bowel movements was (6.75±1.24) times/day and (4.18±1.00) times/day at 3 months and 12 months after surgery. The overall Cleveland quality of life assessment (CGQL) was (0.85±0.08) and (0.92±0.06).

Conclusion

For patients with UC for elective surgery, one-stage IPAA treatment is safe and feasible, and the postoperative defecation function and quality of life are satisfactory.

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