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中华结直肠疾病电子杂志 ›› 2019, Vol. 08 ›› Issue (02) : 120 -124. doi: 10.3877/cma.j.issn.2095-3224.2019.02.003

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青年专家论坛

中日韩中低位直肠癌术前放化疗的理念与策略
申占龙1, 叶颖江1,(), 王锡山2,()   
  1. 1. 100044 北京大学人民医院胃肠外科
    2. 100021 北京,国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院结直肠外科
  • 收稿日期:2018-10-17 出版日期:2019-04-25
  • 通信作者: 叶颖江, 王锡山
  • 基金资助:
    国家自然科学基金面上项目(No.81672375)

Concept and strategy of preoperative chemoradiation for mid-low rectal cancer in China, Japan and Korea

Zhanlong Shen1, Yingjiang Ye1,(), Xishan Wang2,()   

  1. 1. Department of Gastroenterological Surgery, Peking University People′s Hospital, Beijing 100044, China
    2. Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences, Beijing 100021, China
引用本文:

申占龙, 叶颖江, 王锡山. 中日韩中低位直肠癌术前放化疗的理念与策略[J]. 中华结直肠疾病电子杂志, 2019, 08(02): 120-124.

Zhanlong Shen, Yingjiang Ye, Xishan Wang. Concept and strategy of preoperative chemoradiation for mid-low rectal cancer in China, Japan and Korea[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2019, 08(02): 120-124.

关于术前放化疗在中低位直肠癌治疗中选择的理念和策略,中日韩三个国家的医生有些不同。中国的指南接近于美国国立综合癌症网络(National Comprehensive Cancer Network,NCCN)指南,建议对于T3和(或)N+以上的可切除直肠癌患者,推荐术前放化疗;日本大多数医生对可切除的中低位直肠癌并不积极推荐术前放化疗,根据日本指南推荐,对于腹膜返折下局部进展期直肠癌的标准治疗方式为全直肠系膜切除术+侧方淋巴结清扫术;韩国的结直肠癌临床实践指南对术前放化疗的推荐与中国和美国指南类似,与中国不同的是,源于韩国政府的法定政策,韩国医生针对直肠癌患者术前放化疗开展的更为积极。

Concept and strategy are different in preoperative chemoradiation for mid-low rectal cancer between China, Japan and Korea. Chinese guideline for rectal cancer is similar with American guideline of National Comprehensive Cancer Network (NCCN), which recommend that the tumor with preoperative staging more than T3/N+ should be got preoperative chemoradiation; most of Japanese doctors don′t choose preoperative chemoradiation for mid-low rectal cancer, Japanese guideline recommended that standard strategy for local advanced rectal cancer locating below peritoneal reflection should be perform total mesorectal excision plus lateral lymph node dissection; Korean guideline for rectal cancer is similar with Chinese and American guideline, but the difference with Chinese situation is that Korean doctors recommend more patients to get preoperative chemoradiation according to strict Korean government policy.

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