MDT strategy for liver and para-aortic lymph node oligometastasis in colorectal cancer

doi:10.3877/cma.j.issn.2095-3224.2017.04.014

Abstract

Abstract:

Colorectal cancer is one of the most common malignant tumors, the morbidity and mortality rank the forefront of cancers.Metastasis is one of the main factors of poor prognosis in colorectal cancer. The common metastatic sites are the liver, lung and lymph node system, and the liver is one of the most important target organ. For the colorectal cancer metastatic lesions, multidisciplinary team (MDT) is the best choice for treatment.With the progress of multidisciplinary diagnosis and treatment, colorectal cancer ″Oligometastasis″, was gradually raised. The oligometastasis refers to a period in which the tumor is less invasive and has a transitional stage between the primary lesion and the extensive metastasis, the number of metastatic lesions is limited and the metastatic organ is specific.In this study, the MDT treatment strategies of two cases of colorectal cancer patients with synchronous liver metastases (one case with synchronous para-aortic lymph node metastasis) are analyzed and the concept of liver and PALN oligometastasis in colorectal cancer and the progress of treatment are reviewed.

Key words: Colorectal neoplasms, Neoplasm Metastasis, Liver oligometastasis, Para-aortic lymph node oligometastasis, Multidisciplinary team

Chaoyang Gu, Xiangbing Deng, Ziqiang Wang. MDT strategy for liver and para-aortic lymph node oligometastasis in colorectal cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2017, 06(04): 330-335.

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References 34

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	转移部位	转移时间	新辅助治疗	手术方式	辅助治疗	局部无复发生存（月）	全身无复发生存（月）
病例1	肝脏	同时性	4周期mFOLFOX6	原发灶切除+侧方LN清扫+肝脏肿瘤切除、消融	1周期mFOLFOX6	>13	>13
病例2	肝脏、PALN	同时性	3周期mFOLFOX6	原发灶切除+ PALND+肝脏肿瘤切除	7周期mFOLFOX6	>16	>16

	转移部位	转移时间	新辅助治疗	手术方式	辅助治疗	局部无复发生存（月）	全身无复发生存（月）
病例1	肝脏	同时性	4周期mFOLFOX6	原发灶切除+侧方LN清扫+肝脏肿瘤切除、消融	1周期mFOLFOX6	>13	>13
病例2	肝脏、PALN	同时性	3周期mFOLFOX6	原发灶切除+ PALND+肝脏肿瘤切除	7周期mFOLFOX6	>16	>16

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