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中华结直肠疾病电子杂志 ›› 2022, Vol. 11 ›› Issue (04) : 325 -328. doi: 10.3877/cma.j.issn.2095-3224.2022.04.009

综述

结直肠癌黏液腺癌临床病理及治疗进展
邓朝林1, 吴斌1,()   
  1. 1. 100730 中国医学科学院北京协和医学院 北京协和医院基本外科
  • 收稿日期:2022-03-16 出版日期:2022-08-25
  • 通信作者: 吴斌
  • 基金资助:
    中国医学科学院中央级公益性科研院所基本科研业务费专项资金(2021-JKCS-006)

Mucinous colorectal adenocarcinoma: clinical pathology and treatment progress

Chaolin Deng1, Bin. Wu1()   

  1. 1. Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • Received:2022-03-16 Published:2022-08-25
  • Corresponding author: Bin. Wu
引用本文:

邓朝林, 吴斌. 结直肠癌黏液腺癌临床病理及治疗进展[J/OL]. 中华结直肠疾病电子杂志, 2022, 11(04): 325-328.

Chaolin Deng, Bin. Wu. Mucinous colorectal adenocarcinoma: clinical pathology and treatment progress[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2022, 11(04): 325-328.

黏液腺癌作为结直肠腺癌的一个特殊病理亚型,具备特殊的组织病理学特征,在肿瘤的生长、复发转移模式与腺癌具有明显差异。黏液腺癌对目前基于腺癌的治疗方案相对不敏感,临床预后较差。治疗效果的差异及个体化治疗理念的快速发展引起临床医生对黏液亚型的关注。本综述通过对黏液腺癌组织病理学特征的回顾,结合结直肠癌治疗的新进展对结直肠黏液腺癌进行了系统阐述。

Mucinous colorectal adenocarcinoma is a distinct subtype of colorectal adenocarcinoma with characteristic histopathologic features, exhibiting unique patterns of tumor growth, metastasis, and recurrence. Mucinous adenocarcinoma is insensitive to the current adenocarcinoma-based treatment strategy and with poor prognosis. The rapid of development of concepts with individualized treatment have led clinicians to focus on mucinous subtypes. In this review, we discuss the histopathology of mucinous colorectal adenocarcinoma and provide an update on its prognosis and therapeutics from recent literature.

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