切换至 "中华医学电子期刊资源库"

中华结直肠疾病电子杂志 ›› 2022, Vol. 11 ›› Issue (03) : 246 -253. doi: 10.3877/cma.j.issn.2095-3224.2022.03.010

NOSES专栏

腹腔镜结直肠癌NOSES术中左结肠动脉的外科解剖与保留技巧
李佳俊1, 易波2, 郑阳春2,(), 张轲2, 芮元祎2, 许培培2, 赵滨2, 付川川2   
  1. 1. 610051 成都医学院第二附属医院-核工业四一六医院胃肠外科;610041 成都,四川省肿瘤医院结直肠外科
    2. 610041 成都,四川省肿瘤医院结直肠外科
  • 收稿日期:2022-04-16 出版日期:2022-06-25
  • 通信作者: 郑阳春
  • 基金资助:
    四川省科技厅创新团队资助课题(2017TD0029)

Surgical anatomy and preservation techniques of left colic artery in laparoscopic colorectal cancer NOSES surgery

Jiajun Li1, Bo Yi2, Yangchun Zheng2,(), Ke Zhang2, Yuanyi Rui2, Peipei Xu2, Bin Zhao2, Chuanchuan Fu2   

  1. 1. Department of Gastrointestinal Surgery, 416 Hospital of Nuclear Industry, Second Affiliated Hospital of Chengdu Medical College, Chengdu 610051, China; Department of Colorectal Surgery, Sichuan Cancer Hospital, Chengdu 610041, China
    2. Department of Colorectal Surgery, Sichuan Cancer Hospital, Chengdu 610041, China
  • Received:2022-04-16 Published:2022-06-25
  • Corresponding author: Yangchun Zheng
引用本文:

李佳俊, 易波, 郑阳春, 张轲, 芮元祎, 许培培, 赵滨, 付川川. 腹腔镜结直肠癌NOSES术中左结肠动脉的外科解剖与保留技巧[J]. 中华结直肠疾病电子杂志, 2022, 11(03): 246-253.

Jiajun Li, Bo Yi, Yangchun Zheng, Ke Zhang, Yuanyi Rui, Peipei Xu, Bin Zhao, Chuanchuan Fu. Surgical anatomy and preservation techniques of left colic artery in laparoscopic colorectal cancer NOSES surgery[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2022, 11(03): 246-253.

目的

观察腹腔镜结直肠癌经自然腔道取标本手术(NOSES)中左结肠动脉(LCA)的外科解剖,探讨保留LCA的手术技巧及临床疗效。

方法

回顾性分析2017年1月至2021年12月于四川省肿瘤医院施行腹腔镜下保留LCA的结直肠癌NOSES手术85例患者的临床资料,其中54例术中对LCA的外科解剖进行了观察与记录,结合手术录像分析LCA的外科走行与解剖分型,探讨保留LCA的操作技巧和临床效果。

结果

所有病例LCA均从肠系膜下动脉(IMA)左侧发出,LCA发出处至IMA根部的平均距离为(3.5±1.1)cm;75.9%(41/54)病例LCA向外走行时自肠系膜下静脉(IMV)前方与其相交,24.1%(13/54)自IMV后方与其相交;LCA自IMA单独发出者(Ⅰ型)23例(42.6%),LCA与乙状结肠动脉(SA)两支共干者(Ⅱ型)9例(16.7%),LCA与SA、直肠上动脉(SRA)三支共干者(Ⅲ型)19例(35.2%),LCA、SRA与两支或两支以上SA多支共干者(Ⅳ型)3例(5.6%),本组未见LCA缺如病例。85例患者均顺利完成手术,其中2例(2.4%)术后出现了吻合口漏,1例经保守治疗痊愈,1例进行了回肠造瘘手术;无围手术期死亡病例;术后平均住院时间(10.4±3.4)d。

结论

LCA的外科走行多样,解剖变异复杂;腹腔镜下保留LCA需要较高的手术技巧、精细解剖、耐心操作。腹腔镜结直肠癌术中保留LCA操作与NOSES技术相结合,有望将损伤控制、功能保护、微创治疗的外科理念发挥到极致。

Objective

To observe the surgical anatomy of the left colic artery (LCA) during laparoscopic natural orifice specimen extraction surgery (NOSES) for colorectal cancer and to explore the preservation techniques during surgery and its clinical efficacy on patients.

Methods

The clinical data of 85 patients with colorectal cancer who underwent laparoscopic LCA-preserving NOSES operation in Sichuan Cancer Hospital from January 2017 to December 2021 were retrospectively analyzed. Among them, LCA anatomy of 54 patients was observed and recorded, combined with the operation video, the anatomical course and surgical classification of LCA were analyzed, and the operation skills and clinical effect of preserving LCA were discussed.

Results

From all cases, we observed that the LCA emanated from the left side of the inferior mesenteric artery (IMA), and the average distance was about (3.5±1.1) cm from the root of the IMA to the emanation of LCA; Among them, 75.9% (41/54) cases, the LCA intersected in front of the IMV when it traveled outward, and 24.1% (13/54) cases crossed from the rear; twenty-three cases had the LCA branching from the IMA alone (type Ⅰ, 42.6%); nine cases had the LCA co-truncating with the sigmoid artery (SA) (type Ⅱ, 16.7%), nineteen cases had the LCA co-truncating with the superior rectal artery (SRA) and SA (type Ⅲ, 35.2%), and 3 cases had the LCA co-truncating with SRA and two or more SA (type Ⅳ, 5.6%). No absence of LCA was found in this group. All operations performed on 85 patients were successfully completed. Two patients (2.4%) developed anastomotic leakage after surgery, one was cured by conservative treatment, and the other underwent ileostomy. No mortality occurred. The average hospital stay after surgery was (10.4±3.4) days.

Conclusions

The surgical route of LCA is diverse, and its anatomical variation is complex. Preservation of LCA during laparoscopic surgery requires high surgical skills. However, the combination of LCA-preserving operation and NOSES technology during laparoscopic colorectal cancer surgery is expected to maximize the surgical concepts of damage control, function protection, and minimally invasion.

图1 腹腔镜下保留LCA五步法操作示意图。1A:LCA与IMV先伴行再相交,1B:LCA与IMV直接相交不伴行
图2 腹腔镜结直肠癌NOSES术中不同手术方式。2A:NOSES Ⅳ式,2B:NOSES Ⅱ式,2C:NOSES Ⅰ式B法;2D:NOSES Ⅰ式E法
图3 肠系膜下动脉分支类型。3A:LCA作为第一分支自IMA单独发出(Ⅰ型);3B:LCA与SA两支共干(Ⅱ型);3C:LCA与SR、SRA三支共干(Ⅲ型);3D:LCA、SRA与两支SA四支共干(Ⅳ型)
[1]
王锡山. 中国NOSES面临的挑战与展望[J/CD]. 中华结直肠疾病电子杂志, 2018, 7(1): 2-7.
[2]
Lange MM, Buunen M, van de Velde CJ, et al. Level of arterial ligation in rectal cancer surgery: low tie preferred over high tie. A review[J]. Dis Colon Rectum, 2008, 51(7): 1139-1145.
[3]
Nayeri M, Iskander O, Tabchouri N, et al. Low tie compared to high tie vascular ligation of the inferior mesenteric artery in rectal cancer surgery decreases postoperative complications without affecting overall survival[J]. Anticancer Res, 2019, 39(8): 4363-4370.
[4]
Murono K, Kawai K, Kazama S, et al. Anatomy of the inferior mesenteric artery evaluated using 3-dimensional CT angiography[J]. Dis Colon Rectum, 2015, 58(2): 214-219.
[5]
Ke J, Cai J, Wen X, et al. Anatomic variations of inferior mesenteric artery and left colic artery evaluated by 3-dimensional CT angiography: Insights into rectal cancer surgery-A retrospective observational study[J]. Int J Surg, 2017, 41: 106-111.
[6]
李杰, 周颖, 芮元祎, 等. 腹腔镜下结直肠癌标本体内切除经直肠拖出手术的关键操作技巧(附手术视频)[J]. 中国临床新医学, 2019, 12(11): 1159-1162.
[7]
中国NOSES联盟, 中国医师协会结直肠肿瘤专业委员会NOSES专委会. 结直肠肿瘤经自然腔道取标本手术专家共识(2019版)[J/CD]. 中华结直肠疾病电子杂志, 2019, 8(4): 336-342.
[8]
王锡山. 肿瘤外科微创技术的前进方向[J]. 肿瘤学杂志, 2021, 27(6): 421-425.
[9]
王锡山. 结直肠肿瘤NOSES术关键问题的思考与探索[J/CD]. 中华结直肠疾病电子杂志, 2018, 7(4): 315-319.
[10]
Bonnet S, Berger A, Hentati N, et al. High tie versus low tie vascular ligation of the inferior mesenteric artery in colorectal cancer surgery: impact on the gain in colon length and implications on the feasibility of anastomoses[J]. Dis Colon Rectum, 2012, 55(5): 515-521.
[11]
Lee KH, Kim JS, Kim JY. Feasibility and oncologic safety of low ligation of inferior mesenteric artery with D3 dissection in cT3N0M0 sigmoid colon cancer[J]. Ann Surg Treat Res, 2018, 94(4): 209-215.
[12]
Zeng J, Su G. High ligation of the inferior mesenteric artery during sigmoid colon and rectal cancer surgery increases the risk of anastomotic leakage: a meta-analysis[J]. World J Surg Oncol, 2018, 16(1):157.
[13]
中华医学会外科学分会结直肠外科学组. 中国直肠癌手术吻合口漏诊断、预防及处理专家共识(2019版)[J]. 中华胃肠外科杂志, 2019, 22(3): 201-206.
[14]
中华人民共和国国家卫生健康委员会. 中国结直肠癌诊疗规范(2020年版)[J]. 中华外科杂志, 2020, 58(8): 561-585.
[15]
Kobayashi M, Morishita S, Okabayashi T, et al. Preoperative assessment of vascular anatomy of inferior mesenteric artery by volume-rendered 3D-CT for laparoscopic lymph node dissection with left colic artery preservation in lower sigmoid and rectal cancer[J]. World J Gastroenterol, 2006, 12(4): 553-555.
[16]
陈纲, 李世拥. 腹腔镜直肠癌根治保留左结肠血管的技巧及意义[J/CD]. 中华普外科手术学杂志(电子版), 2018, 12(1): 9-11.
[17]
Sakorafas GH, Zouros E, Peros G. Applied vascular anatomy of the colon and rectum: clinical implications for the surgical oncologist[J]. Surg Oncol, 2006, 15(4): 243-255.
[18]
Yada H, Sawai K, Taniguchi H, et al. Analysis of vascular anatomy and lymph node metastases warrants radical segmental bowel resection for colon cancer[J]. World J Surg, 1997, 21(1): 109-115.
[19]
沈海玉, 刘正, 陈佳楠, 等. 血管三维重建技术在腹腔镜保留左结肠动脉的直肠癌低位前切除术的临床应用研究[J/OL]. 中华结直肠疾病电子杂志, 2021, 10(2): 137-143.
[20]
燕速, 马新福, 赵康, 等. 低位直肠癌常规行No.253淋巴结清扫的争议与共识[J]. 中国实用外科杂志, 2020, 40(3): 315-322.
[21]
李杰, 李禹呈, 郑阳春, 等. 腹腔镜下结直肠癌体内切除标本经直肠拖出手术(NOSES)的无菌和无瘤操作技巧[J/CD]. 中华腔镜外科杂志(电子版), 2018, 11(6): 360-363.
[1] 康夏, 田浩, 钱进, 高源, 缪洪明, 齐晓伟. 骨织素抑制破骨细胞分化改善肿瘤骨转移中骨溶解的机制研究[J]. 中华乳腺病杂志(电子版), 2023, 17(06): 329-339.
[2] 代莉, 邓恢伟, 郭华静, 黄芙蓉. 术中持续输注艾司氯胺酮对腹腔镜结直肠癌手术患者术后睡眠质量的影响[J]. 中华普通外科学文献(电子版), 2023, 17(06): 408-412.
[3] 王得晨, 杨康, 杨自杰, 归明彬, 屈莲平, 张小凤, 高峰. 结直肠癌微卫星稳定状态和程序性死亡、吲哚胺2,3-双加氧酶关系的研究进展[J]. 中华普通外科学文献(电子版), 2023, 17(06): 462-465.
[4] 唐旭, 韩冰, 刘威, 陈茹星. 结直肠癌根治术后隐匿性肝转移危险因素分析及预测模型构建[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 16-20.
[5] 张生军, 赵阿静, 李守博, 郝祥宏, 刘敏丽. 高糖通过HGF/c-met通路促进结直肠癌侵袭和迁移的实验研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 21-24.
[6] 王春荣, 陈姜, 喻晨. 循Glisson蒂鞘外解剖、Laennec膜入路腹腔镜解剖性左半肝切除术临床应用[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 37-40.
[7] 李婷, 张琳. 血清脂肪酸代谢物及维生素D水平与结直肠癌发生的关系研究[J]. 中华普外科手术学杂志(电子版), 2023, 17(06): 661-665.
[8] 陈纲, 李涛, 李世拥. 腹腔镜下保留左结肠动脉的低位直肠癌根治术[J]. 中华普外科手术学杂志(电子版), 2023, 17(05): 485-485.
[9] 张起尧, 刘子文. 复杂腹壁疝的解剖和生物力学基础[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 674-676.
[10] 李博, 胡刚, 邱文龙, 汤坚强, 王锡山. 多功能吲哚菁绿近红外荧光血管成像技术在腹腔镜直肠癌经自然腔道取标本手术(NOSES Ⅳ式)中的应用(附视频)[J]. 中华结直肠疾病电子杂志, 2023, 12(06): 524-528.
[11] 倪文凯, 齐翀, 许小丹, 周燮程, 殷庆章, 蔡元坤. 结直肠癌患者术后发生延迟性肠麻痹的影响因素分析[J]. 中华结直肠疾病电子杂志, 2023, 12(06): 484-489.
[12] 范小彧, 孙司正, 鄂一民, 喻春钊. 梗阻性左半结肠癌不同手术治疗方案的选择应用[J]. 中华结直肠疾病电子杂志, 2023, 12(06): 500-504.
[13] 关旭, 王锡山. 基于外科与免疫视角思考结直肠癌区域淋巴结处理的功与过[J]. 中华结直肠疾病电子杂志, 2023, 12(06): 448-452.
[14] 顾睿祈, 方洪生, 蔡国响. 循环肿瘤DNA检测在结直肠癌诊治中的应用与进展[J]. 中华结直肠疾病电子杂志, 2023, 12(06): 453-459.
[15] 张继新, 胡军红, 谢爽, 武祖印, 张春旭. 经阴道单孔腹腔镜阑尾切除术可行性及近期疗效分析[J]. 中华结直肠疾病电子杂志, 2023, 12(06): 460-465.
阅读次数
全文


摘要