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中华结直肠疾病电子杂志

中华结直肠疾病电子杂志 ›› 2016, Vol. 05 ›› Issue (06) : 503 -506. doi: 10.3877/cma.j.issn.2095-3224.2016.06.010

所属专题： 经典病例； 文献；

论著

Ⅰ期结直肠癌局部复发与转移18例患者的临床病理特征分析
汪毅1, 王杰1, 许东奎1, 刘骞2,†()   
  1. 1. 100021　北京，国家癌症中心/中国医学科学院北京协和医学院肿瘤医院VIP病房
    2. 100021　北京，国家癌症中心/中国医学科学院北京协和医学院肿瘤医院结直肠外科
  • 收稿日期:2016-09-11 出版日期:2016-12-25
  • 通信作者: 刘骞

Analysis of 18 cases of Stage I colorectal cancer: before and after local relapse and distant metastasis

Yi Wang1, Jie Wang1, Dongkui Xu1, Qian Liu2,†()   

  1. 1. Department of VIP, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
    2. Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  • Received:2016-09-11 Published:2016-12-25
  • Corresponding author: Qian Liu
  • About author:
    Corresponding author: Liu Qian, Email:
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引用本文：

汪毅, 王杰, 许东奎, 刘骞. Ⅰ期结直肠癌局部复发与转移18例患者的临床病理特征分析[J]. 中华结直肠疾病电子杂志, 2016, 05(06): 503-506.

Yi Wang, Jie Wang, Dongkui Xu, Qian Liu. Analysis of 18 cases of Stage I colorectal cancer: before and after local relapse and distant metastasis[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 05(06): 503-506.

目的

探讨早期结直肠癌复发与转移的高危因素、诊断与治疗现状，以期改善预后。

方法

回顾性总结2005年3月至2008年5月中国医学科学院肿瘤医院收治的18例Ⅰ期、无脉管瘤栓与神经侵犯但出现复发及转移的结直肠癌患者临床病理资料。

结果

18例Ⅰ期局部复发与远处转移的结直肠癌患者中，男性12例（66.7%），女性6例（33.3%），术前便血15例（83.3%），无体重减轻11例（64.7%），T1肿瘤2例（11.1%），T2肿瘤16例（88.9%），局部复发7例（38.9%），远处转移9例（50.0%），淋巴结转移2例（11.1%）。11例患者（61.11%）的复发与转移没有临床症状。复发转移后中位生存期为57.6个月。

结论

Ⅰ期结直肠癌患者必须常规进行定期复查，要重视复发与转移的早期症状。

关键词: 结直肠肿瘤, 诊断, 复发与转移, 高危因素
Objective

To discuss the high-risk factor, diagnosis and treatment of the relapse of stage I (T1-T2) colorectal cancer.

Methods

We retrospectively analyzed the clinical and pathological factors of 18 cases stage I (T1~T2) colorectal cancer from March 2005 to May 2008 at Cancer Hospital Chinese Academy of Medical Sciences, all the 18 cases were without high-risk features such as lymphovascular invasion, perineural invasion.

Results

Among the 18 patients, 12 (66.7%) were males and 6 (33.3%) were females. Before operation, 15 patients had hemafecia, and 7 patients lost weight. Final histology revealed 2 (11.1%) lesions to be T1 and 16 (88.9%) T2 cancers. 7 patients (38.9%) had local recurrence , and 9 patients (50.0%) had distant metastases, while 2 cases (11.1%) had lymph nodes metastases. After relapse, 11 cases (61.11%) had no symptoms. Among these patients, the mean overall survival was 57.6 months.

Conclusions

Regular postoperative surveillance in stage I colorectal cancer is very important . It′s necessary to pay attention to their early symptoms after relapse. Early diagnosis, active treatment could potentially lead to an improvement in outcome.

Key words: Colorectal neoplasms, Diagnosis, Local relapse and distant metastasis, High risk factor
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