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中华结直肠疾病电子杂志 ›› 2016, Vol. 05 ›› Issue (02) : 148 -152. doi: 10.3877/cma.j.issn.2095-3224.2016.02.07

所属专题: 文献

论著

肛管静息压与短暂肛门括约肌松弛的临床研究
尹淑慧1, 丁健华1, 赵玉涓1, 卓光鑚1, 张斌1, 冯滢滢1, 赵勇1, 赵克1,()   
  1. 1. 100088 北京,火箭军总医院结直肠肛门外科
  • 收稿日期:2016-01-14 出版日期:2016-04-25
  • 通信作者: 赵克
  • 基金资助:
    首都临床特色应用研究课题(Z151100004015013)

Clinical research of anal canal resting pressure and transient anal sphincter relaxations

Shuhui Yin1, Jianhua Ding1, Yujuan Zhao1, Guangzuan Zhuo1, Bin Zhang1, Yingying Feng1, Yong Zhao1, Ke Zhao1,()   

  1. 1. Department of Colorectal Surgery, The General Hospital of the PLA Rocket Force, Beijing 100088, China
  • Received:2016-01-14 Published:2016-04-25
  • Corresponding author: Ke Zhao
  • About author:
    Corresponding author: Zhao Ke, Email:
引用本文:

尹淑慧, 丁健华, 赵玉涓, 卓光鑚, 张斌, 冯滢滢, 赵勇, 赵克. 肛管静息压与短暂肛门括约肌松弛的临床研究[J]. 中华结直肠疾病电子杂志, 2016, 05(02): 148-152.

Shuhui Yin, Jianhua Ding, Yujuan Zhao, Guangzuan Zhuo, Bin Zhang, Yingying Feng, Yong Zhao, Ke Zhao. Clinical research of anal canal resting pressure and transient anal sphincter relaxations[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 05(02): 148-152.

目的

明确静息状态下短暂肛门括约肌松弛(transient anal sphincter relaxations,TASRs)的出现规律,与肛管静息压(anal resting pressure,ARP)的关系,探讨TASRs的病理生理意义以及在这种情况下如何准确完成肛门直肠测压。

方法

对2015年1月1日~10月31日期间来我科进行测压检查的便秘患者33例,肛门潮湿瘙痒患者13例,健康志愿者13例进行肛门直肠测压检查,延长肛管静息压检测时间至15 min,对测压资料进行分析。

结果

15 min内三组均有TASRs出现(10/13、19/33、11/13)且出现比例差异无统计学意义(P>0.05),在静息压高于60 mmHg时TASRs更容易出现(39/41),TASRs的出现组与不出现组的肛管长度(2.71±0.89 vs 2.32±1.05)、初感觉容量(51.8±32.52 vs 63.0±36.64)差异无统计学意义(P>0.05),RAIR的抑制深度(54.28±16.81 vs 40.46±10.68)差异有统计学意义(P<0.05)。

结论

TASRs较普遍存在,从而导致静息压处于一个波动的范围内,建议静息压按范围取值,并在不同时段进行不同的测压检测项。TASRs与RAIR可能具有同质性,TASRs大多数属于正常生理现象,少数过于深大的TASRs可能具有病理意义,并且部分能被感知。

Objective

To investigate the laws of transient anal sphincter relaxations (TASRs) appearing in resting state, and its relationship with anal resting pressure.To explore the pathophysiological significance of TASRs and how to complete anorectal manometry accurately in this situation.

Methods

From January 1 to October 31 in 2015, 33 constipated patients, 13 anal moist and pruritus ani patients, 13 healthy volunteers received anorectal manometry, detection time of anal resting pressure were prolonged to 15min, all manometry data were analyzed.

Results

Within 15min TASRs appeared in all three groups (10/13, 19/33, 11/13) and the proportion appeared no difference (P>0.05); When resting pressure above 60mmHg TASRs were more prone to appear (39/41). In the two groups with and without TASRs, there were no difference between anal length (2.71 ± 0.89 vs 2.32 ± 1.05) and first sensory capacity (51.8 ± 32.52 vs 63.0 ± 36.64) (P>0.05), but the differences were significant between depth of RAIR inhibition (54.28 ± 16.81 vs 40.46 ± 10.68) (P<0.05).

Conclusions

TASRs are very common and make ARP in a range of a fluctuation, we recommend recording ARP by a range value and at different time different manometry carried. TASRs and RAIR are likely homogeneous, mostly TASRs are normal physiological phenomenon, few deep TASRs may have pathological significance, and some of which can be perceived.

表1 三组出现TASRs的人数统计表
表2 TASRs是否出现者按静息压最高值进行区分表
表3 肛管高压区长度、初感觉容量、RAIR抑制率比较表(±s
图2 该患者在15 min内出现3次TASRs(箭头所示),松弛最明显时肛管静息压降至7.8 mmHg(松弛率86%)。在这种情况下直肠压很容易超过肛管压,导致自知或不自知的肠液渗漏。注:每横格高度代表0~100 mmHg,图1,2来源于同一患者
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