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中华结直肠疾病电子杂志 ›› 2016, Vol. 05 ›› Issue (02) : 121 -126. doi: 10.3877/cma.j.issn.2095-3224.2016.02.03

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胰腺癌放疗剂量模式改变的研究进展
任刚1, 夏廷毅1,()   
  1. 1. 100142 北京,中国人民解放军空军总医院肿瘤放疗科
  • 收稿日期:2016-02-10 出版日期:2016-04-25
  • 通信作者: 夏廷毅
  • 基金资助:
    首都卫生发展科研专项联合攻关项目(2014-1-5124)

Research progress of radiotherapy dose pattern changes for pancreatic cancer

Gang Ren1, Tingyi Xia1,()   

  1. 1. Department of Radiation Oncology, PLA Air Force General Hospital, Beijing 100142, China
  • Received:2016-02-10 Published:2016-04-25
  • Corresponding author: Tingyi Xia
  • About author:
    Corresponding author: Xia Tingyi, Email:
引用本文:

任刚, 夏廷毅. 胰腺癌放疗剂量模式改变的研究进展[J/OL]. 中华结直肠疾病电子杂志, 2016, 05(02): 121-126.

Gang Ren, Tingyi Xia. Research progress of radiotherapy dose pattern changes for pancreatic cancer[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 05(02): 121-126.

胰腺癌恶性程度高,预后差。放射治疗是胰腺癌的重要治疗手段,但常规剂量模式延长患者生存时间的疗效受到质疑。通过改变胰腺癌放疗剂量模式,国内外文献报道采用高剂量少分次模式可提高肿瘤局部控制率、缓解癌痛,并有进一步延长患者生存时间的趋势。尽管如此,在高剂量少分次放疗中剂量模式的选取、危及器官的保护、以及如何与手术联合等方面仍有待深入研究。

Pancreatic cancer is a highly malignant tumor and the prognosis is poor. Radiotherapy is an important treatment for pancreatic cancer. But the curative effect of the conventional dose mode to prolong the survival time of the patients is questioned. By changing dose model of radiotherapy, hypofractionated mode can improve the local control rate of the tumor, relieve pain, and maybe prolong the survival time in domestic and foreign literatures. In spite of this, the selection of the dose pattern, the protection of the organ, and how to combine with the operation in the high dose and low dose radiotherapy still need further explored.

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