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中华结直肠疾病电子杂志 ›› 2016, Vol. 05 ›› Issue (02) : 127 -132. doi: 10.3877/cma.j.issn.2095-3224.2016.02.04

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直肠癌术前放疗进展
万觉锋1, 章真1,()   
  1. 1. 200032 上海,复旦大学附属肿瘤医院放疗科;复旦大学上海医学院肿瘤学系
  • 收稿日期:2016-01-02 出版日期:2016-04-25
  • 通信作者: 章真
  • 基金资助:
    国家自然科学基金(81372432)

Advances in preoperative radiation of locally advanced rectal cancer

Juefeng Wan1, Zhen Zhang1,()   

  1. 1. Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Received:2016-01-02 Published:2016-04-25
  • Corresponding author: Zhen Zhang
  • About author:
    Corresponding author: Zhang Zhen, Email:
引用本文:

万觉锋, 章真. 直肠癌术前放疗进展[J]. 中华结直肠疾病电子杂志, 2016, 05(02): 127-132.

Juefeng Wan, Zhen Zhang. Advances in preoperative radiation of locally advanced rectal cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 05(02): 127-132.

2004年德国CAO/ARO/AIO-94临床研究奠定了局部晚期直肠癌术前新辅助放化的治疗策略。近年来,全世界对于如何进一步提高放化疗疗效和个体化治疗在放疗同期药物配比、新辅助放化疗前加入诱导化疗、延长新辅助放化疗至手术间隔期、放化疗后器官保留和中国患者适应性等五方面进行了探索,本文将对上述方面进行阐述。

Neoadjuvant chemoradiation combined with radical surgery has been established as the standard care for locally advanced rectal cancer after the randomized phase III clinical trial CAO/ARO/AIO-94 in 2004. This paper reviewed advances in chemotherapy combined with radiation, neoadjuvant chemotherapy before chemoradiaiton, prolonging the interval between chemoradiaiton and surgery, organ preservation after chemoradiaiton and adaptability of Chinese patients which have all contributed to improvements of efficacy of chemoradiaiton and individualized treatment.

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