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Chinese Journal of Colorectal Diseases(Electronic Edition) ›› 2025, Vol. 14 ›› Issue (02): 174-178. doi: 10.3877/cma.j.issn.2095-3224.2025.02.010

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Research progress of gut microbiota in radiation enteritis and its treatment

Yangyang Xiao1, Jiaqu Cui2, Zuoxi Huang1, Jian Li1, Chuanwen Liao1,()   

  1. 1. Department of Gastrointestinal Surgery,Jiangxi Provincial People's Hospital,The First Affiliated Hospital of Nanchang Medical College,Nanchang 330006,China
    2. Intestinal Microenvironment Treatment Center of General Surgery,Shanghai Tenth People's Hospital,Tongji University School of Medicine,Shanghai 200072,China
  • Received:2024-11-15 Online:2025-04-25 Published:2025-05-12
  • Contact: Chuanwen Liao

Abstract:

Radiation enteritis (RE) refers to the intestinal complications caused by radiation therapy for malignant tumors in the pelvic,abdominal,or retroperitoneal regions,and is one of the common complications in clinical radiation therapy. The gut microbiota is closely related to human health,and many studies support the crucial role of gut microbiota in the occurrence and development of RE. By regulating the balance of microbiota,the goal of preventing and assisting in the treatment of RE can be achieved. The author focuses on summarizing the relationship and related mechanisms between gut microbiota and RE,and explores the application of gut microbiota therapy in the clinical treatment of RE.

Key words: Gut microbiota, Radiation enteritis, Fecal microbiota transplantation

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