Research progress on the involvement of bile acids in colon inflammation and colon cancer

doi:10.3877/cma.j.issn.2095-3224.2021.02.014

Abstract

Abstract:

The occurrence and development of colorectal cancer are related to many factors, among which bile acid has been paid more and more attention. Human bile acids form a physiological and non-toxic bile acid pool mediated by related factors. Although bile acid-related metabolism has complex relationship with intestinal inflammation, the mechanism of bile acid in the development of colon cancer is not clear. This article reviews the relationship between bile acid and colon inflammation and malignant tumor.

Key words: Colorectal neoplasms, Inflammatory bowel cancer, bile acid, Secondary bile acids, Bile acid receptor

Tianyi Ma, Xishan Wang. Research progress on the involvement of bile acids in colon inflammation and colon cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2021, 10(02): 201-204.

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