Cancer prevention and treatment is an important measure to realize the strategy of "Healthy China 2030" and maintain the health of the general public. In order to help achieve the grand goal of the Healthy China strategy, in the field of colorectal cancer, we should analyze and sort out the epidemiological characteristics of colorectal cancer in China, compare with developed countries, discover the characteristics of colorectal cancer in China, identify the gaps between China and developed countries in prevention and treatment, and then make targeted efforts to strengthen the relevant work. This paper combines the 2018 China Annual Tumor Registry Report and compares it with Cancer Statistics, 2019 and Colorectal Cancer Statistics, 2020 published by the American Cancer Society to analyze the epidemiological characteristics of colorectal cancer in both countries. epidemiological characteristics of colorectal cancer in both countries. Overall, compared with the decreasing incidence and mortality rates of colorectal cancer in the United States year by year, the incidence and mortality rates of colorectal cancer in China are still slowly increasing in recent years. Both countries show a trend of younger incidence. The proportion of rectal cancer incidence in China is much higher than that in developed countries. Men, urban and eastern regions are still the key population and regions for colorectal cancer prevention and treatment. In this paper, we also analyze the necessity and importance of early diagnosis and treatment of colorectal cancer in China from three strategic levels: national, social and individual.