Analysis of 18 cases of Stage I colorectal cancer: before and after local relapse and distant metastasis

doi:10.3877/cma.j.issn.2095-3224.2016.06.010

Chinese Journal of Colorectal Diseases(Electronic Edition) ›› 2016, Vol. 05 ›› Issue (06): 503-506. doi: 10.3877/cma.j.issn.2095-3224.2016.06.010

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• Original Article • Previous Articles Next Articles

Analysis of 18 cases of Stage I colorectal cancer: before and after local relapse and distant metastasis

Yi Wang¹, Jie Wang¹, Dongkui Xu¹, Qian Liu²^,^†()

^1. Department of VIP, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
^2. Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Received:2016-09-11 Online:2016-12-25 Published:2016-12-25
Contact: Qian Liu
About author:
Corresponding author: Liu Qian, Email: fcwpumch@163.com

Abstract

Abstract:

Objective

To discuss the high-risk factor, diagnosis and treatment of the relapse of stage I (T1-T2) colorectal cancer.

Methods

We retrospectively analyzed the clinical and pathological factors of 18 cases stage I (T1~T2) colorectal cancer from March 2005 to May 2008 at Cancer Hospital Chinese Academy of Medical Sciences, all the 18 cases were without high-risk features such as lymphovascular invasion, perineural invasion.

Results

Among the 18 patients, 12 (66.7%) were males and 6 (33.3%) were females. Before operation, 15 patients had hemafecia, and 7 patients lost weight. Final histology revealed 2 (11.1%) lesions to be T1 and 16 (88.9%) T2 cancers. 7 patients (38.9%) had local recurrence , and 9 patients (50.0%) had distant metastases, while 2 cases (11.1%) had lymph nodes metastases. After relapse, 11 cases (61.11%) had no symptoms. Among these patients, the mean overall survival was 57.6 months.

Conclusions

Regular postoperative surveillance in stage I colorectal cancer is very important . It′s necessary to pay attention to their early symptoms after relapse. Early diagnosis, active treatment could potentially lead to an improvement in outcome.

Key words: Colorectal neoplasms, Diagnosis, Local relapse and distant metastasis, High risk factor

Yi Wang, Jie Wang, Dongkui Xu, Qian Liu. Analysis of 18 cases of Stage I colorectal cancer: before and after local relapse and distant metastasis[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 05(06): 503-506.

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