Abstract:

Among the patients with locally advanced colon cancer, the patients with tumor infiltrating the bladder have a poor prognosis. With the progress of technology and the update of treatment concepts, the diagnosis and treatment methods of locally advanced colon cancer are introduced. In terms of diagnosis, the diagnostic methods currently carried out include urine red blood cell test, pelvic or intracavitary B-ultrasound, cystoscopy, pelvic CT or MRI enhanced scan, intraoperative or postoperative pathological diagnosis, etc. Among them, gross hematuria, cystoscopy, and CT examination are better diagnostic methods for finding bladder infiltration. In terms of treatment, surgery is the main treatment for locally advanced colon cancer, and preoperative neoadjuvant therapy is the current treatment focus. In surgery, clinicians should choose between partial cystectomy and total cystectomy based on preoperative evaluation and other factors. At present, most scholars believe that R0 resection and prevention of local intravesical recurrence are the key factors to consider in the selection of surgical methods for patients with colon cancer infiltrating bladder. In terms of perioperative drug therapy, there are also many research advances in neoadjuvant therapy and adjuvant therapy, and the key link of drug therapy is the screening of suitable population. This review is expected to provide reference for clinicians in the diagnosis and treatment of patients with locally advanced colon cancer.

Key words: Colonic neoplasms, Bladder invasion, Preoperative diagnosis, Perioperative treatment, Research progress