Clinical observation of the treatment of 42 cases with slow transit constipation by improving intestinal microcirculation

doi:10.3877/cma.j.issn.2095-3224.2014.05.06

Abstract

Abstract:

Objective

To observe the clinical effects of Cinepazide Maleate and compound danshen injection on treating slow transit constipation.

Method

42 cases of slow transit constipation were selected and injected with Cinepazide Maleate once a day and for 14 days as a treatment cycle.The symptoms, impervious X-ray marker residue and adverse reactions were observed before and after the treatment.

Results

After 14 days, Bristol score was significantly lower after treatment, the difference was statistically significant(P<0.05), intestinal residue markers was significantly reduced than before, the difference was statistically significant(P<0.05). The total effective rate was 78.25%, and there was no obvious adverse reaction.

Conclusion

Cinepazide Maleate and danshen compound injection had significantly clinical effects on treating slow transit constipation by improving the intestinal microcirculation, reducing the intestinal vascular resistance, increasing blood flow, promoting intestinal peristalsis and enhancing bowel power transmission.

Key words: Constipation, Microcirculation, Danshen injection, Cinepazide maleate

Shi-wei YANG, Fu-Qian LI, Xue-zhi XIN. Clinical observation of the treatment of 42 cases with slow transit constipation by improving intestinal microcirculation[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2014, 03(05): 338-340.

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Figures/Tables 1

References 15

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组别	例数	治疗前	治疗后
24 h	42	18.6±2.6	15.1±5.5^*
48 h	42	16.8±3.8	5.9±6.6^*
72 h	42	14.3±5.3	0.8±1.3^*

组别	例数	治疗前	治疗后
24 h	42	18.6±2.6	15.1±5.5^*
48 h	42	16.8±3.8	5.9±6.6^*
72 h	42	14.3±5.3	0.8±1.3^*

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