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中华结直肠疾病电子杂志 ›› 2018, Vol. 07 ›› Issue (03) : 270 -275. doi: 10.3877/cma.j.issn.2095-3224.2018.03.015

所属专题: 文献

综述

麻醉对肿瘤患者免疫功能及术后肿瘤复发和转移的影响
吴蔽野1, 郑晖1,()   
  1. 1. 100021 北京,国家癌症中心/中国医学科学院北京协和医学院肿瘤医院麻醉科
  • 收稿日期:2017-12-09 出版日期:2018-06-25
  • 通信作者: 郑晖
  • 基金资助:
    中国医学科学院肿瘤医院人才发展经费奖励项目(No.N04165)

Effects of anesthesia on the immune system of tumor patients and postoperative period malignant tumor recurrence and metastasis

Biye Wu1, Hui Zheng1,()   

  1. 1. Department of Anesthesiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  • Received:2017-12-09 Published:2018-06-25
  • Corresponding author: Hui Zheng
  • About author:
    Corresponding author: Zheng Hui, Email:
引用本文:

吴蔽野, 郑晖. 麻醉对肿瘤患者免疫功能及术后肿瘤复发和转移的影响[J]. 中华结直肠疾病电子杂志, 2018, 07(03): 270-275.

Biye Wu, Hui Zheng. Effects of anesthesia on the immune system of tumor patients and postoperative period malignant tumor recurrence and metastasis[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2018, 07(03): 270-275.

近年来,肿瘤发生率明显上升,目前手术仍是治疗多种恶性肿瘤的主要方式。术后原发肿瘤的复发和转移是患者预后不良的主要原因之一。研究表明患者自身免疫系统功能与肿瘤的发生发展相互作用。麻醉作为围术期不可或缺的一部分,与患者免疫系统功能及术后肿瘤复发转移之间存在复杂关联。本文阐述了多种麻醉方式和麻醉药物与肿瘤患者免疫功能的相互作用及对肿瘤患者术后转移和复发的影响。

In recent years, the incidence of tumor has risen apparently, and for most of malignant tumor patients, they undergo surgical procedures. The recurrence and metastasis of primary tumor after operation is one of the main causes of poor prognosis. Studies show that the function of the patient′s immune system is interacting with the development of the tumor. As an integral part of the perioperative period, anesthesia has a complex relationship with the immune system and the recurrence and metastasis of the malignant tumor during the postoperative period. In this review, we describe the effects of various anesthetic methods and narcotic drugs on the immune system of the tumor patients and the postoperative metastasis and recurrence of tumor patients.

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