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中华结直肠疾病电子杂志 ›› 2018, Vol. 07 ›› Issue (03) : 266 -269. doi: 10.3877/cma.j.issn.2095-3224.2018.03.014

所属专题: 文献

综述

直肠癌术后吻合口漏危险因素的研究现状
潘博1, 董明1,()   
  1. 1. 110001 沈阳,中国医科大学附属第一医院胃肠外科
  • 收稿日期:2017-04-23 出版日期:2018-06-25
  • 通信作者: 董明

Research status of risk factors of anastomotic leakage after resection of rectal cancer

Bo Pan1, Ming Dong1,()   

  1. 1. Department of Gastrointestinal Surgery, First Affiliated Hospital, China Medical University, Shenyang 110001, China
  • Received:2017-04-23 Published:2018-06-25
  • Corresponding author: Ming Dong
  • About author:
    Corresponding author: Dong Ming, Email:
引用本文:

潘博, 董明. 直肠癌术后吻合口漏危险因素的研究现状[J/OL]. 中华结直肠疾病电子杂志, 2018, 07(03): 266-269.

Bo Pan, Ming Dong. Research status of risk factors of anastomotic leakage after resection of rectal cancer[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2018, 07(03): 266-269.

吻合口漏是直肠癌术后严重的并发症之一,增加患者术后死亡率及其他并发症的发生率。近年来有大量研究探讨吻合口漏的危险因素,然而某些结果尚存在争议,本研究针对直肠癌术后吻合口漏的危险因素进行综述。

Anastomotic leakage is one of the most serious complications after rectal cancer surgery, which increases the incidence of postoperative mortality and other complications. In recent years, a large number of studies have been carried out to explore the risk factors of anastomotic leakage. However, some results are still controversial. In this review, we will discuss the risk factors of anastomotic leakage after rectal cancer surgery.

[1]
Rahbari NN, Weitz J, Hohenberger W, et al. Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer [J]. Surgery, 2010, 147(3): 339-351.
[2]
Akagi T, Inomata M, Etoh T, et al. Multivariate evaluation of the technical difficulties in performing laparoscopic anterior resection for rectal cancer [J]. Surg Laparosc Endosc Percutan Tech, 2012, 22(1): 52-57.
[3]
Maggiori L, Bretagnol F, Lefevre JH, et al. Conservative management is associated with a decreased risk of definitive stoma after anastomotic leakage complicating sphincter-saving resection for rectal cancer [J]. Colorectal Dis, 2011, 13(6): 632-637.
[4]
Qu H, Liu Y, Bi DS. Clinical risk factors for anastomotic leakage after laparoscopic anterior resection for rectal cancer: a systematic review and meta-analysis [J]. Surg Endosc, 2015, 29(12): 3608-3617.
[5]
Garlipp B, Ptok H, Schmidt U, et al. Neoadjuvant chemoradiotherapy for rectal carcinoma: effects on anastomotic leak rate and postoperative bladder dysfunction after non-emergency sphincter-preserving anterior rectal resection. Results of the Quality Assurance in Rectal Cancer Surgery multicenter observational trial [J]. Langenbecks Arch Surg, 2010, 395(8): 1031-1038.
[6]
Hu MH, Huang RK, Zhao RS, et al. Does neoadjuvant therapy increase the incidence of anastomotic leakage after anterior resection for mid and low rectal cancer? A systematic review and meta-analysis [J]. Colorectal Dis, 2017, 19(1): 16-26.
[7]
Eriksen TF, Lassen CB, Gogenur I. Treatment with corticosteroids and the risk of anastomotic leakage following lower gastrointestinal surgery: a literature survey [J]. Colorectal Dis, 2014, 16(5): O154-160.
[8]
Ostenfeld EB, Erichsen R, Baron JA, et al.Preadmission glucocorticoid use and anastomotic leakage after colon and rectal cancer resections: a Danish cohort study [J]. BMJ Open, 2015, 5(9): e008045.
[9]
Ji WB, Hahn KY, Kwak JM, et al. Mechanical Bowel Preparation Does Not Affect Clinical Severity of Anastomotic Leakage in Rectal Cancer Surgery [J]. World J Surg, 2017, 41(5): 1366-1374.
[10]
Courtney DE, Kelly ME, Burke JP, et al. Postoperative outcomes following mechanical bowel preparation before proctectomy: a meta-analysis [J]. Colorectal Dis, 2015, 17(10): 862-869.
[11]
Scarborough JE, Mantyh CR, Sun Z. Combined Mechanical and Oral Antibiotic Bowel Preparation Reduces Incisional Surgical Site Infection and Anastomotic Leak Rates After Elective Colorectal Resection: An Analysis of Colectomy-Targeted ACS NSQIP [J]. Ann Surg, 2015, 262(2): 331-337.
[12]
Lustosa SA, Matos D, Atallah AN, et al. Stapled versus handsewn methods for colorectal anastomosis surgery: a systematic review of randomized controlled trials [J]. Sao Paulo Med J, 2002, 120(5): 132-136.
[13]
Shekarriz H, Eigenwald J, Shekarriz B, et al. Anastomotic leak in colorectal surgery: are 75 % preventable [J]. Int J Colorectal Dis, 2015, 30(11): 1525-1531.
[14]
Yun JA, Cho YB, Park YA, et al. Clinical manifestations and risk factors of anastomotic leakage after low anterior resection for rectal cancer [J]. ANZ J Surg, 2015, 87(11): 908.
[15]
Akiyoshi T, Ueno M, Fukunaga Y, et al. Incidence of and risk factors for anastomotic leakage after laparoscopic anterior resection with intracorporeal rectal transection and double-stapling technique anastomosis for rectal cancer [J]. Am J Surg, 2011, 202(3): 259-264.
[16]
Tan WS, Tang CL, Shi L, et al. Meta-analysis of defunctioning stomas in low anterior resection for rectal cancer [J]. Br J Surg, 2009, 96(11): 462-472.
[17]
Kang CY, Halabi WJ, Chaudhry OO, et al. Risk Factors for Anastomotic Leakage After Anterior Resection for Rectal Cancer [J]. JAMA Surg, 2013, 148(1): 65.
[18]
Reilly F, Burke JP, Appelmans E, et al. Incidence, risks and outcome of radiological leak following early contrast enema after anterior resection [J]. Int J Colorectal Dis, 2014, 29(4): 453-458.
[19]
王鸿鹄,徐昊,王振宁, 等. 低位直肠癌保肛患者行预防性回肠末端造瘘的优缺点 [J]. 中华结直肠疾病电子杂志,2015, 4(1): 78-80.
[20]
刘维波, 邹德龄, 王怀帅, 等. 直肠癌前切除术吻合口漏术中预防策略 [J]. 中华结直肠疾病电子杂志, 2014, 3(3): 198-199.
[21]
Vermeer TA, Orsini RG, Daams F, et al. Anastomotic leakage and presacral abscess formation after locally advanced rectal cancer surgery: Incidence, risk factors and treatment [J]. Eur J Surg Oncol, 2014, 40(11): 1502-1509.
[22]
Rondelli F, Bugiantella W, Vedovati MC, et al. To drain or not to drain extraperitoneal colorectal anastomosis? A systematic review and meta-analysis [J]. Colorectal Dis, 2014, 16(2): O35-42.
[23]
Zhang HY, Zhao CL, Xie J, et al. To drain or not to drain in colorectal anastomosis: a meta-analysis [J]. Int J Colorectal Dis, 2016, 31(5): 951-960.
[24]
Trencheva K, Morrissey KP, Wells M, et al. Identifying Important Predictors for Anastomotic Leak After Colon and Rectal Resection: prospective study on 616 patients [J]. Ann Surg, 2013, 257(1): 108-113.
[25]
Rutegård M, Westermark S, Kverneng Hultberg D, et al. Non-Steroidal Anti-Inflammatory Drug Use and Risk of Anastomotic Leakage after Anterior Resection: A Protocol-Based Study [J]. Dig Surg, 2016, 33(2): 129-135.
[26]
Klein M, Gögenur I.Postoperative use of non-steroidal anti-inflammatory drugs in patients with anastomotic leakage requiring reoperation after colorectal resection: cohort study based on prospective data [J]. BMJ, 2012, 345: e6166.
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