切换至 "中华医学电子期刊资源库"

中华结直肠疾病电子杂志 ›› 2018, Vol. 07 ›› Issue (01) : 70 -73. doi: 10.3877/cma.j.issn.2095-3224.2018.01.015

所属专题: 文献

综述

结直肠癌脑转移的临床现状及诊疗进展
袁子茗1, 王贵玉1, 王锡山2,()   
  1. 1. 150086 哈尔滨医科大学附属第二医院结直肠肿瘤外科
    2. 100021 北京,国家癌症中心/中国医学科学院北京协和医学院肿瘤医院结直肠外科
  • 收稿日期:2017-03-03 出版日期:2018-02-25
  • 通信作者: 王锡山
  • 基金资助:
    国家自然科学基金面上项目(No.81572930); 中国医学科学院肿瘤医院学科带头人奖励基金(No.RC2016003); 国家重点研发计划精准医学研究专项(No.2016YFC0905300); 中国医学科学院医学与健康科技创新工程项目(No.2016-I2M-1-001)

Diagnosis and treatment progress and current clinical situation of brain metastases from colorectal cancer

Ziming Yuan1, Guiyu Wang1, Xishan Wang2,()   

  1. 1. Department of Colorectal Cancer Surgery, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, China
    2. Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  • Received:2017-03-03 Published:2018-02-25
  • Corresponding author: Xishan Wang
  • About author:
    Corresponding author: Wang Xishan, Email:
引用本文:

袁子茗, 王贵玉, 王锡山. 结直肠癌脑转移的临床现状及诊疗进展[J/OL]. 中华结直肠疾病电子杂志, 2018, 07(01): 70-73.

Ziming Yuan, Guiyu Wang, Xishan Wang. Diagnosis and treatment progress and current clinical situation of brain metastases from colorectal cancer[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2018, 07(01): 70-73.

结直肠癌(CRC)是目前威胁人类健康以及生命的常见恶性肿瘤之一,复发和转移是治疗失败甚至导致患者死亡的最主要原因。结直肠癌远处转移最常见的部位为肝脏,其次为肺脏。随着影像技术的不断提升,结直肠癌脑转移(BM)的发病率逐年升高,为最大程度的延长患者生存期,提升结直肠癌患者终末期的诊疗水平刻不容缓。本文将从结直肠癌脑转移的临床特征、相关诊疗方案等方面进行阐述总结,望对今后的临床诊治提供些许帮助。

Colorectal cancer (CRC) is one of the most common malignancies that threaten to human health and life. Relapse and metastasis are the main causes of the treatment failure and even death. Liver is the most common metastasizing place, and then lung. With the development of the imaging techniques, the incidence of the brain metastases (BM) form colorectal cancer increases year by year. So it is urgent for us to improve the diagnosis and treatment of patients in end-stage, prolong the lifetime as far as possible. In this article, we summarized the clinical characteristics, diagnosis and treatments therapies, hoping to provide some help in clinical therapies.

[1]
Sundermayer ML, Meropol NJ, Rogatko A, et al. Changing patterns of bone and brain metastases in patients with colorectal cancer [J]. Clin Colorectal Cancer, 2005, 5(2): 108-113.
[2]
Go PH, Klaassen Z, Meadows MC, et al. Gastrointestinal cancer and brain metastasis: a rare and ominous sign [J]. Cancer, 2011, 117(16): 3630-3640.
[3]
Mongan JP, Fadul CE, Cole BF, et al. Brain metastases from colorectal cancer: risk factors, incidence, and the possible role of chemokines [J]. Clin Colorectal Cancer, 2009, 8(2): 100-105.
[4]
Yano S, Shinohara H, Herbst RS, et al. Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis [J]. Cancer Res, 2000, 60(17): 4959-4967.
[5]
Tanaka M, Omura K, Watanabe Y, et al. Prognostic factors of colorectal cancer: K-ras mutation, overexpression of the p53 protein, and cell proliferative activity [J]. J Surg Oncol, 1994, 57(1): 57-64.
[6]
Chu C, Navalkissoor S, Gillmore R, et al. Neurological symptoms from a brain metastasis as the first presentation of colorectal cancer [J]. BMJ Case Rep, 2015, pii: bcr2015210422.
[7]
吕毛古,黄秀昌,黄伟.颅脑转移瘤的CT特征[J]. 医学影像学杂志, 2014, 14(10): 796-798.
[8]
Gu XD, Cai YT, Zhou YM, et al. Prognostic factors and multidisciplinary treatment modalities for brain metastases from colorectal cancer: analysis of 93 patients [J]. BMC Cancer, 2015, 15(1): 902-907.
[9]
Kye BH, Kim HJ, Kang WK, et al. Brain metastases from colorectal cancer: the role of surgical resection in selected patients [J]. Colorectal Dis, 2012, 14(7): e378-385.
[10]
Noura S, Ohue M, Shingai T, et al. Brain metastasis from colorectal cancer: prognostic factors and survival [J]. J Surg Oncol, 2012, 106(2): 144-148.
[11]
王雅坤,王晰程,沈琳, 等.结直肠癌脑转移的临床特征及诊断治疗[J]. 中国肿瘤临床, 2016, 43(21): 962-966.
[12]
Peng QP, Feng QQ, Ke CQ. Clinical study of brain metastasis from digestive system neoplasms [J]. Chin Clin Oncol, 2014, 19(1): 69-71.
[13]
Zhang X, Zhang W, Cao WD, et al. A review of current management of brain metastases [J]. Ann Surg Oncol, 2012, 19(3): 1043-1050.
[14]
Matsunaga S, Shuto T, Kawahara N, et al. Gamma Knife surgery for brain metastases from colorectal cancer [J]. J Neurosurg, 2011, 114(3): 782-789.
[1] 王亚红, 蔡胜, 葛志通, 杨筱, 李建初. 颅骨骨膜窦的超声表现一例[J/OL]. 中华医学超声杂志(电子版), 2024, 21(11): 1089-1091.
[2] 史学兵, 谢迎东, 谢霓, 徐超丽, 杨斌, 孙帼. 声辐射力弹性成像对不可切除肝细胞癌门静脉癌栓患者放射治疗效果的评价[J/OL]. 中华医学超声杂志(电子版), 2024, 21(08): 778-784.
[3] 易柏成, 李旭光, 王容容, 王新璇. 数字化3D打印导板应用于上前牙钙化根管治疗2例[J/OL]. 中华口腔医学研究杂志(电子版), 2024, 18(06): 385-390.
[4] 李华志, 曹广, 刘殿刚, 张雅静. 不同入路下行肝切除术治疗原发性肝细胞癌的临床对比[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 52-55.
[5] 徐逸男. 不同术式治疗梗阻性左半结直肠癌的疗效观察[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 72-75.
[6] 陈浩, 王萌. 胃印戒细胞癌的临床病理特征及治疗选择的研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 108-111.
[7] 刘柏隆, 周祥福. 压力性尿失禁阶梯治疗的项目介绍[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 125-125.
[8] 刘柏隆. 女性压力性尿失禁阶梯治疗之手术治疗方案选择[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 126-126.
[9] 王秋生. 胆道良性疾病诊疗策略[J/OL]. 中华肝脏外科手术学电子杂志, 2024, 13(06): 779-782.
[10] 李浩, 陈棋帅, 费发珠, 张宁伟, 李元东, 王硕晨, 任宾. 慢性肝病肝纤维化无创诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(09): 863-867.
[11] 谭瑞义. 小细胞骨肉瘤诊断及治疗研究现状与进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(08): 781-784.
[12] 王誉英, 刘世伟, 王睿, 曾娅玲, 涂禧慧, 张蒲蓉. 老年乳腺癌新辅助治疗病理完全缓解的预测因素分析[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 641-646.
[13] 王子阳, 王宏宾, 刘晓旌. 血清标志物对甲胎蛋白阴性肝细胞癌诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 677-681.
[14] 陈慧, 邹祖鹏, 周田田, 张艺丹, 张海萍. 皮肤镜对头皮红斑性皮肤病辅助鉴别诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 692-698.
[15] 崔军威, 蔡华丽, 胡艺冰, 胡慧. 亚甲蓝联合金属定位夹及定位钩针标记在乳腺癌辅助化疗后评估腋窝转移淋巴结的临床应用价值探究[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 625-632.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?