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中华结直肠疾病电子杂志 ›› 2017, Vol. 06 ›› Issue (02) : 135 -138. doi: 10.3877/cma.j.issn.2095-3224.2017.02.011

所属专题: 文献

综述

液体活检在常见肿瘤中的应用
杨延巍1, 刘彦虹1,()   
  1. 1. 150086 哈尔滨医科大学附属第二医院检验科
  • 收稿日期:2017-01-19 出版日期:2017-04-25
  • 通信作者: 刘彦虹

The application of liquid biopsy in common tumors

Yanwei Yang1, Yanhong Liu1,()   

  1. 1. Department of Clinical Laboratory, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China
  • Received:2017-01-19 Published:2017-04-25
  • Corresponding author: Yanhong Liu
  • About author:
    Corresponding author: Liu Yanhong, Email:
引用本文:

杨延巍, 刘彦虹. 液体活检在常见肿瘤中的应用[J]. 中华结直肠疾病电子杂志, 2017, 06(02): 135-138.

Yanwei Yang, Yanhong Liu. The application of liquid biopsy in common tumors[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2017, 06(02): 135-138.

目前治疗肿瘤的手段多种多样,已经不完全局限于传统的手术切除及放化疗等,分子靶向治疗药物的普及使"精准医学"正逐步被应用到临床肿瘤领域。肿瘤精准医学将个体疾病的遗传学信息、诊断、治疗三者结合,使肿瘤的诊治更具有针对性、靶向性和特异性。液体活检是一种新兴的无创检测技术,该项技术是通过采集患者体液(包括血液、唾液、汗液及分泌物等)对体内的肿瘤或移植器官状态进行监测的方法。了解和临床应用这项检测技术对肿瘤的诊断尤为凸显。本文综述了液体活检的生物学特性及其在常见肿瘤精准治疗的应用。

Nowadays, there are many different methods for the treatment of cancer, such as traditional surgical resection and radiotherapy and chemotherapy. The popularization of molecular targeted therapy drugs has gradually been applied to the field of clinical oncology. Tumor precision medicine can combine with individual disease genetic information, diagnosis and treatment, so that the diagnosis and treatment of cancer is more targeting and specificity. Liquid biopsy is a new noninvasive detection technique that is used to monitor the state of a tumor or transplanted organ in a patient by collecting body fluid (including blood, saliva, sweat, and secretions). Knowing and applying this detection technology in clinical is particularly prominent in the diagnosis of the tumor. This paper reviewed the biological characteristics of liquid biopsy and its application in the treatment of common tumors.

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