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中华结直肠疾病电子杂志 ›› 2017, Vol. 06 ›› Issue (01) : 15 -20. doi: 10.3877/cma.j.issn.2095-3224.2017.01.004

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青年专家论坛

浅谈加速康复外科模式下术前口服碳水化合物在结直肠外科中的应用及可能机制
王治国1,()   
  1. 1. 200003 上海第二军医大学附属长征医院结直肠肛门外科
  • 收稿日期:2016-12-27 出版日期:2017-02-25
  • 通信作者: 王治国
  • 基金资助:
    国家自然基金青年基金资助项目(No.81000845)

Analysis of the application and potential mechanism about the preoperative oral carbohydrate in colorectal surgery for ERAS mode

Zhiguo Wang1,()   

  1. 1. Department of Colorectal & Anal Surgery, Shanghai Chang Zheng Hospital, Second Military Medical University, Shanghai 200003, China
  • Received:2016-12-27 Published:2017-02-25
  • Corresponding author: Zhiguo Wang
  • About author:
    Corresponding author: Wang Zhiguo, Email:
引用本文:

王治国. 浅谈加速康复外科模式下术前口服碳水化合物在结直肠外科中的应用及可能机制[J]. 中华结直肠疾病电子杂志, 2017, 06(01): 15-20.

Zhiguo Wang. Analysis of the application and potential mechanism about the preoperative oral carbohydrate in colorectal surgery for ERAS mode[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2017, 06(01): 15-20.

加速康复外科(ERAS)是指在围手术期采用多模式处理措施以提高临床预后。结直肠手术创伤导致机体产生一系列生理和心理应激,最终发生术后胰岛素抵抗。术后胰岛素抵抗是结直肠癌手术引发代谢反应的中心环节,它可增加术后并发症发生率和死亡率,其早期纠正与预后直接相关。术前口服碳水化合物方法可以改善结直肠外科手术术后机体的胰岛素抵抗,是重要的术前代谢调控方法之一。

Enhanced recovery after surgery (ERAS) represents a multimodal approach to improve the outcomes of medical treatment and care. Colorectal surgery initiates a series of physiological and psychological stress processes in the body, inducing transient insulin resistance. Insulin resistance is a central metabolic response to surgery and it has been shown to increase morbidity and mortality after surgery. Thus its early detection and remedy would directly lead to great improvement of outcomes. Preoperative intake of oral carbohydrates for ERAS has resulted in attenuating the development of postoperative insulin resistance and being one of the important methods of preoperative metabolic regulation in colorectal surgery.

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