To compare the difference of CT manifestations of left-sided and right-sided colon mucinous adenocarcinoma, and to improve the radiology acknowledge about them.

CT findings of 168 patients with colorectal mucinous adenocarcinoma confirmed by surgery and pathology were retrospectively analyzed in the Tumor Hospital of Yunnan Province, the differences of age, gender, length and thickness of the involved intestinal wall, the thickening pattern of the intestinal wall, the peri-intestinal invasion, CT value on NECT, CT value on CECT, the contrast-enhanced form, degree of low density region in CECT, the occurrence metastasis of lymph node and other organs were compared between the two groups.

Compared with the left-sided colon mucinous adenocarcinoma group, lesions of right-sided colon mucinous adenocarcinoma group was wider and thicker (t=5.066、3.903, P<0.05). There were statistically significant differences of the thickening pattern of the intestinal wall (χ²=15.398, P<0.05), peri-intestinal invasion (χ²=9.954, P=0.007), contrast-enhanced level (χ²=9.641, P=0.008) and low density region in enhanced CT show (χ²=12.946, P=0.002) between the two groups, while there was no statistically significant difference in age, CT value on NECT, CT value on CECT, gender, lymph node metastasis and other organs metastasis (t=0.029、0.0108、1.494, χ²=0.148、0.391、0.910, P>0.05).

There are some differences of CT manifestations of left-sided and right-sided colon mucinous adenocarcinoma. Compared with left-sided colon mucinous adenocarcinoma, the CT manifestations of right-sided colon mucinous adenocarcinoma include a wider and thicker of bowel wall thickening with the lower enhancement degree and more cystic components in contrast-enhanced CT show.