The relationship among colorectal cancer, obesity and other etiologies

doi:10.3877/cma.j.issn.2095-3224.2016.04.008

Abstract

Abstract:

Objective

Obesity is associated with increased risk of colorectal cancer. This study was aiming to explore the relationship between BMI and colon cancer for prevention and treatment.

Methods

Clinical data including BMI of 202 colorectal cancer patients and 202 healthy population from Tai′an Central Hospital were analyzed.

Results

The mean BMI was significantly higher in colorectal cancer patients than in healthy populatioin (25.1±3.5 kg/m², 21.2±3.1 kg/m², t=-12.153, P<0.001). When stratified by sex (P<0.05), cholecystopathy (P<0.05), the BMI was always higher in colon cancer patients than in healthy group. Logistic regression analyses showed that BMI (t=12.171, P<0.001), cholecystopathy (t=3.128, P=0.002) and sex (t=3.321, P=0.001) were important risk factors of colon cancer. The diabetes mellitus (t=1.260, P=0.208) and age (t=-1.790, P=0.074) are not associated with colorectal cancer.

Conclusion

The occurrence of colorectal cancer is related to BMI, cholecystopathy and sex.

Key words: Colorectal neoplasms, Obesity, Body mass index

Huijing Yao, Haipeng Yuan. The relationship among colorectal cancer, obesity and other etiologies[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 05(04): 319-322.

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Figures/Tables 9

References 10

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组别	例数	BMI 1组	BMI 2组	BMI 3组	BMI 4组
研究组	129	12（9.3）	29（22.5）	59（45.7）	29（22.5）
对照组	99	25（25.3）	52（52.5）	16（16.2）	6（6.1）
χ²值	?	65.735
P值	?	P<0.01

组别	例数	BMI 1组	BMI 2组	BMI 3组	BMI 4组
研究组	129	12（9.3）	29（22.5）	59（45.7）	29（22.5）
对照组	99	25（25.3）	52（52.5）	16（16.2）	6（6.1）
χ²值	?	65.735
P值	?	P<0.01

组别	例数	BMI 1组	BMI 2组	BMI 3组	BMI 4组
研究组	73	0（0）	11（15.1）	39（53.4）	23（31.5）
对照组	103	27（26.2）	60（58.3）	14（13.6）	2（1.9）
χ²值	?	68.911
P值	?	P<0.01

组别	例数	BMI 1组	BMI 2组	BMI 3组	BMI 4组
研究组	73	0（0）	11（15.1）	39（53.4）	23（31.5）
对照组	103	27（26.2）	60（58.3）	14（13.6）	2（1.9）
χ²值	?	68.911
P值	?	P<0.01

组别	例数	BMI 1组	BMI 2组	BMI 3组	BMI 4组
研究组	73	9（12.3）	38（52.1）	23（31.5）	3（4.1）
对照组	109	48（44.0）	57（52.3）	3（2.8）	1（0.9）
χ²	?	41.366
P值	?	P<0.01

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