A new perspective on signaling pathway level selection of colorectal cancer cell lines

doi:10.3877/cma.j.issn.2095-3224.2025.02.011

Abstract

Abstract:

Objective

To provide a new strategy for selecting colorectal cancer cell lines that are compatible with the research objectives.

Methods

The transcriptome results of Berg et al. were analyzed using pathway variation analysis to characterize the pathway features of different colorectal cancer cell lines.

Results

Different cell lines exhibit diverse cancer pathway features. Similar pathway preferences may still exist between different subtypes of colorectal cancer cell lines.

Conclusion

The selection of colorectal cancer cell lines has great research value and we provides with a new perspective on the biological behavior of tumor cell lines.

Key words: Transcriptomics, Colorectal cancer cell line, Signal path enrichment analysis

Fei Wang, Kai Zhang, Zhansheng Yao. A new perspective on signaling pathway level selection of colorectal cancer cell lines[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2025, 14(02): 179-183.

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URL: https://zhjzcjbdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-3224.2025.02.011

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Figures/Tables 3

References 14

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