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Chinese Journal of Colorectal Diseases(Electronic Edition) ›› 2021, Vol. 10 ›› Issue (04): 379-384. doi: 10.3877/cma.j.issn.2095-3224.2021.04.008

• Original Article • Previous Articles     Next Articles

Clinical study on the management of wounds after high complex anal fistula operation by sucking-irrigation balance method of traditional Chinese medicine

Haoyue Zhang1, Yang Zhang1,(), Yehuang Wang1   

  1. 1. Colorectal Disease Center of Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing 210000, China
  • Received:2020-11-02 Online:2021-08-30 Published:2021-09-17
  • Contact: Yang Zhang

Abstract:

Objective

To observe the clinical effect of sucking-irrigation balance method of traditional Chinese medicine in the management of wounds after high complex anal fistula operation.

Methods

Fifty patients with high complex anal fistula were randomly divided into two groups. The test group (25 cases) was treated with sucking-irrigation balance method of traditional Chinese medicine, and the control group (25 cases) was treated with routine dressing (vaseline gauze apply on the wound).

Results

There were no significant differences in age, gender, duration of disease, wound exudation and pain index on the first day after surgery (P>0.05); by the fifth day after operation, the exudation in the test group (36.60±5.48) mL was significantly less than the control group (150.80±12.31) mL (t=42.384, P<0.01). After the negative pressure drainage device was removed, the patients in the test group had a reddish color and dense granules without obvious edema, the average score is (1.40±0.65) points, (0.68±0.80) points, better than the control group (3.04±0.54) points, (2.48±0.51) points, because there is no pain in changing the gauze within 5 days, so the test group pain index (2.88±0.53) points were significantly lower than the control group (4.52±0.77) points (t=3.545, P<0.01). Taking a small amount of wound tissue for CD31 immunohistochemical analysis, the microvessel density of the test group[(22.91±4.00)个/mm2] was shown to be significantly more than the control group[(19.77±2.05)/mm2] (t=3.493, P<0.01). On the 10th day after operation, the patients in the test group had removed the negative pressure drainage device, got rid of the negative pressure attraction state, resumed the routine dressing change, and the wound surface was re-infected by external microorganisms and inflammation. The exudation increased compared with the previous period, with an average of (99.20±5.72) mL, but compared with the control group (114.60±9.46) mL, there was still a statistical difference (t=6.969, P<0.05); during the continuous dressing change, the carrion gradually detached and the new meat grew longer. The quality and speed of granulation growth in the test group were excellent on the 10th and 21st days after surgery. In the control group, the wound granulation color and granulation density score of the test group were (0.60±0.58) and (0.24±0.44) which were lower than those of the control group, and the reduction rate of the wound in the test group on the 14th, 21st, and 28th days after operation were (0.117±0.014), (0.243±0.009), (0.369±0.017) which were faster than the control groups.

Conclusion

The sucking-irrigation balance method of traditional Chinese medicine has a good effect on the management of wounds after high complex anal fistula operation, which can promote wound healing, reduce wound edema, relieve wound pain and reduce the recurrence rate.

Key words: Anal canal, High complex anal fistula, Negative pressure drainage, Traditional Chinese medicine soakage, Wound

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