Research progress of individualized lateral lymph node dissection strategy for advanced low-grade rectal cancer

doi:10.3877/cma.j.issn.2095-3224.2020.03.013

Abstract

Abstract:

Lymphatic drainage in the middle and lower rectum is mainly in the superior and lateral directions. Lateral lymph node metastasis has been confirmed in the middle and lower rectal cancer. However, the current lateral lymph node dissection is controversial. Lateral lymph node dissection (LLND) is not routinely performed in western countries. More emphasis is placed on neoadjuvant chemoradiotherapy (nCRT). The main reason is that western scholars believe that LLND has uncertain oncological effects and high complication rates. However, recent evidence suggests that neoadjuvant therapy combined with total mesorectal excision (TME) may not be sufficient in patients with low-grade rectal cancer in some advanced stages. This article aims to describe the current status and progress of selective lateral lymph node dissection in low- and moderate-grade rectal cancer, and to explore the trend and direction of further treatment of middle and low rectal cancer: selective and individualized lateral lymph node dissection.

Key words: Rectal neoplasms, Total mesorectal excision, Lateral lymph node dissection, Neoadjuvant therapy

Rui Du, Dong Tang, Daorong Wang. Research progress of individualized lateral lymph node dissection strategy for advanced low-grade rectal cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2020, 09(03): 283-287.

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References 39

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