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中华结直肠疾病电子杂志 ›› 2023, Vol. 12 ›› Issue (03) : 253 -259. doi: 10.3877/cma.j.issn.2095-3224.2023.03.013

经验交流

经末段回肠系膜后隧道完成重叠式三角吻合的结肠脾曲癌完全腹腔镜左半结肠切除术23例临床分析
徐正, 苏昊, 包满都拉, 罗寿, 张岳阳, 关旭, 张明光, 赵志勋, 梁建伟, 刘正, 刘骞, 王锡山, 周海涛()   
  1. 100021 北京,国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院结直肠外科
    100142 北京大学肿瘤医院暨北京市肿瘤防治研究所,恶性肿瘤发病机制及转化研究教育部重点实验室胃肠肿瘤中心
    100021 北京,国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院胰胃外科
    518116 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院深圳医院胃肠外科
  • 收稿日期:2022-12-08 出版日期:2023-06-25
  • 通信作者: 周海涛
  • 基金资助:
    国家卫生健康委员会医药卫生科技发展研究中心2021年微创手术临床应用规范研究课题(WA2021RW13); 中国医学科学院医学与健康科技创新工程(重大协调创新项目)(2021-I2M-1-010)

Totally laparoscopic left hemicolectomy with overlapping delta-shaped anastomosis through the tunnel of terminal ileal mesentery: an analysis of 23 cases with splenic flexure cancer

Zheng Xu, Hao Su, Mandula Bao, Shou Luo, Yueyang Zhang, Xu Guan, Mingguang Zhang, Zhixun Zhao, Jianwei Liang, Zheng Liu, Qian Liu, Xishan Wang, Haitao Zhou()   

  1. Department of Colorectal Surgery, National Cancer Center, National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100021, China
    Department of Gastrointestinal Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing 100142, China
    Department of Pancreatic and Gastric Surgery, National Cancer Center, National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100021, China
    Department of Gastrointestinal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, China
  • Received:2022-12-08 Published:2023-06-25
  • Corresponding author: Haitao Zhou
引用本文:

徐正, 苏昊, 包满都拉, 罗寿, 张岳阳, 关旭, 张明光, 赵志勋, 梁建伟, 刘正, 刘骞, 王锡山, 周海涛. 经末段回肠系膜后隧道完成重叠式三角吻合的结肠脾曲癌完全腹腔镜左半结肠切除术23例临床分析[J]. 中华结直肠疾病电子杂志, 2023, 12(03): 253-259.

Zheng Xu, Hao Su, Mandula Bao, Shou Luo, Yueyang Zhang, Xu Guan, Mingguang Zhang, Zhixun Zhao, Jianwei Liang, Zheng Liu, Qian Liu, Xishan Wang, Haitao Zhou. Totally laparoscopic left hemicolectomy with overlapping delta-shaped anastomosis through the tunnel of terminal ileal mesentery: an analysis of 23 cases with splenic flexure cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2023, 12(03): 253-259.

目的

探讨采用经末段回肠系膜后隧道完成重叠式三角吻合的完全腹腔镜左半结肠切除术在结肠脾曲癌外科治疗中的可行性、安全性及近期疗效。

方法

回顾性收集中国医学科学院北京协和医学院肿瘤医院2018年1月至2022年1月收治的结肠脾曲癌患者中,行经末段回肠系膜后隧道完成重叠式三角吻合的完全腹腔镜左半结肠切除手术的23例患者临床和病理资料,统计并分析患者基线资料、手术情况、术后病理情况、术后恢复及围手术期并发症等数据。

结果

23例患者均成功施行经末段回肠系膜后隧道完成腔内吻合的完全腹腔镜左半结肠切除术。中位手术时间165 min,中位术中出血量为40 mL,中位切口长度为5.0 cm。手术标本肿瘤中位长径为4.3 cm,中位近端切缘为13.2 cm,中位远端切缘为12.1 cm,中位淋巴结检出数目为19枚。患者中位术后下地时间、进食时间、排气时间、排便时间与住院时间分别为17.5 h、12 h、33.5 h、55.5 h、5 d。随访30天内,1例患者出现腹腔感染,经抗感染保守治疗后好转。其余患者未出现切口感染、吻合口漏、腹腔出血、肠梗阻等并发症。

结论

经末段回肠系膜后隧道行完全腹腔镜下重叠式三角吻合可应用于结肠脾曲癌患者的外科治疗,安全可行,近期疗效满意,远期疗效待进一步随访观察。

Objective

To explore the short-term outcomes of totally laparoscopic left hemicolectomy with overlapping delta-shaped anastomosis through the tunnel of terminal ileal mesentery in the surgical treatment of splenic flexure cancer.

Methods

We retrospectively collected the 23 patients diagnosed with splenic flexure cancer who underwent the totally laparoscopic left hemicolectomy with overlapping delta-shaped anastomosis through the tunnel of terminal ileal mesentery in National Cancer Center/National Clinical Research Center for Cancer /Cancer Hospital from January 2018 to January 2022. Baseline variables, surgical outcomes, pathological characteristics, postoperative recovery and complications were analyzed.

Results

All patients have successfully undergone the totally laparoscopic left hemicolectomy with overlapping delta-shaped anastomosis through the tunnel of terminal ileal mesentery. The median operation time was 165 min. The median estimated blood loss was 40 mL and the median incisional length was 5.0 cm. With regard to pathological characteristics, the median length of tumor was 4.3 cm. The median proximal and distal resection margin was 13.2 cm and 12.1 cm, respectively. The median time to first ground activities, first oral intake, first flatus passage, first defecation, and postoperative hospital stay were 17.5 h, 12 h, 33.5 h, 55.5 h, 5 d, respectively. One patient suffered from the abdominal infection, which was controlled after antibiotic therapy. Other patients were not suffered from incisional infection, anastomotic leakage, abdominal bleeding or intestinal obstruction during the 30-day follow-up period.

Conclusion

Totally laparoscopic left hemicolectomy with overlapping delta-shaped anastomosis through the tunnel of terminal ileal mesentery could be applied in the surgical treatment of splenic flexure cancer with satisfactory short-term outcomes. But the long-term outcomes need to be explored.

图1 经末段回肠系膜后隧道完成重叠式三角吻合的完全腹腔镜左半结肠切除术手术步骤。1A:结肠中血管左支;1B:切除后的两端肠管不足以直接腔镜下无张力吻合;1C:分离回肠系膜与后腹膜粘连;1D:沿Toldt’s间隙由内向外拓展隧道;1E:将隧道与尾侧游离区域会合贯通;1F:将乙状结肠断端经隧道提至右上腹;1G:横结肠和乙状结肠断端顺向重叠,准备行腔镜下吻合;1H:完成肠管对系膜肠壁的侧侧吻合;1I:闭合肠管共同开口,完成消化道重建
[1]
Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J]. CA Cancer J Clin, 2021, 71(3): 209-249.
[2]
Levien DH, Gibbons S, Begos D, et al. Survival after resection of carcinoma of the splenic flexure [J]. Dis Colon Rectum, 1991, 34(5): 401-403.
[3]
Spenic Flexure Cancer (SFC) Study Group. European multicenter propensity score match study of laparoscopic vs. open colectomy for splenic flexure carcinomas: Results from the Splenic Flexure Cancer (SFC) Study Group [J]. J Visc Surg, 2022, 159(5): 373-382.
[4]
Kim MK, Lee IK, Kang WK, et al. Long-term oncologic outcomes of laparoscopic surgery for splenic flexure colon cancer are comparable to conventional open surgery[J]. Ann Surg Treat Res, 2017, 93(1): 35-42.
[5]
Weiss JM, Pfau PR, O'connor ES, et al. Mortality by stage for right- versus left-sided colon cancer: analysis of surveillance, epidemiology, and end results--Medicare data[J]. J Clin Oncol, 2011, 29(33): 4401-4409.
[6]
Swaid F, Sroka G, Madi H, et al. Totally laparoscopic versus laparoscopic-assisted left colectomy for cancer: a retrospective review[J]. Surg Endosc, 2016, 30(6): 2481-2488.
[7]
Steffen C, Bokey EL, Chapuis PH. Carcinoma of the splenic flexure [J]. Dis Colon Rectum, 1987, 30(11): 872-874.
[8]
Bao MDL, Ge L, Su H, et al. Analysis of short-term efficacy of overlapping delta-shaped anastomosis in totally laparoscopic left hemicolectomy for digestive tract reconstruction[J]. Chin J Gastrointest Surg, 2021, 24(5): 433-439.
[9]
Hajibandeh S, Hajibandeh S, Hussain I, et al. Comparison of extended right hemicolectomy, left hemicolectomy and segmental colectomy for splenic flexure colon cancer: a systematic review and meta-analysis[J]. Colorectal Dis, 2020, 22(12): 1885-1907.
[10]
Cai D, Guan G, Liu X, et al. Clinical analysis on lymph node metastasis pattern in left-sided colon cancers[J]. Chin J Gastrointest Surg, 2016, 19(6): 659-663.
[11]
Wang X, Zheng Z, Chen M, et al. Subtotal colectomy, extended right hemicolectomy, left hemicolectomy, or splenic flexure colectomy for splenic flexure tumors: a network meta-analysis[J]. Int J Colorectal Dis, 2021, 36(2): 311-322.
[12]
Pellino G, Frasson M, García-granero A, et al. Predictors of complications and mortality following left colectomy with primary stapled anastomosis for cancer: results of a multicentric study with 1111 patients[J]. Colorectal Dis, 2018, 20(11): 986-995.
[13]
You YN, Chua HK, Nelson H, et al. Segmental vs. extended colectomy: measurable differences in morbidity, function, and quality of life[J]. Dis Colon Rectum, 2008, 51(7): 1036-1043.
[14]
Lim JF, Ho YH. Total colectomy with ileorectal anastomosis leads to appreciable loss in quality of life irrespective of primary diagnosis[J]. Tech Coloproctol, 2001, 5(2): 79-83.
[15]
Portale G, Popescu GO, Parotto M, et al. Internal hernia after laparoscopic colorectal surgery: an under-reported potentially severe complication. A systematic review and meta-analysis[J]. Surg Endosc, 2019, 33(4): 1066-1074.
[16]
Toh JW, Lim R, Keshava A, et al. The risk of internal hernia or volvulus after laparoscopic colorectal surgery: a systematic review[J]. Colorectal Dis, 2016, 18(12): 1133-1141.
[17]
Taira T, Murono K, Nozawa H, et al. A cross sectional study to investigate internal hernia post left-sided colectomy preserving superior rectal artery[J]. Ann Med Surg (Lond), 2019, 48: 124-128.
[18]
Portale G, Cipollari C, Zuin M, et al. Prevalence of internal hernia following laparoscopic colorectal surgery: single-center report on 1300 patients[J]. Surg Endosc, 2021, 35(8): 4315-4320.
[19]
Toupet A. Intermediate colectomy with transmesenteric angulo-sigmoid anastomosis[J]. Presse Med (1893), 1961, 69: 2693-2694.
[20]
Campanati RG, Hanan B, Gomes Da Silva R. Laparoscopic retroileal pull-through colorectal anastomosis technique[J]. Dis Colon Rectum, 2022, 65(4): e239.
[21]
Rombeau JL, Collins JP, Turnbull RB. Left-sided colectomy with retroileal colorectal anastomosis [J]. Arch Surg, 1978, 113(8): 1004-1005.
[22]
Sakamoto Y, Tokunaga R, Miyamoto Y, et al. Retroileal colorectal anastomosis after extended left colectomy: application for laparoscopic surgery[J]. Surg Today, 2016, 46(12): 1476-1478.
[23]
Dunlavy P, Allan L, Raman S. Totally laparoscopic retroileal transverse colon to rectal anastomosis following extended left colectomy[J]. Dis Colon Rectum, 2017, 60(11): 1224.
[24]
Seow-en I, Ke TW, Chang SC, et al. Laparoscopic retrojejunal trans-mesenteric anastomosis for extended left-sided colorectal resections-a new solution to an old problem[J]. Colorectal Dis, 2021, 23(5): 1262-1267.
[25]
Milone M, Angelini P, Berardi G, et al. Intracorporeal versus extracorporeal anastomosis after laparoscopic left colectomy for splenic flexure cancer: results from a multi-institutional audit on 181 consecutive patients[J]. Surg Endosc, 2018, 32(8): 3467-3473.
[26]
Ge L, Su H, Liang JW, et al. Short-term efficacy of totally laparoscopic left colon cancer radical resection with overlapped delta-shaped anastomosis technique [J]. Chinese Journal of Oncology, 2020, 42(6): 507-512.
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