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中华结直肠疾病电子杂志 ›› 2021, Vol. 10 ›› Issue (02) : 113 -116. doi: 10.3877/cma.j.issn.2095-3224.2021.02.001

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直肠癌微创手术后吻合口漏的微创再手术研究进展
葛琛阳1, 杜金林1,()   
  1. 1. 321000 浙江大学医学院附属金华医院结直肠肛门外科
  • 收稿日期:2021-01-13 出版日期:2021-04-25
  • 通信作者: 杜金林
  • 基金资助:
    浙江省基础公益研究项目(LGF18H160029); 金华市科技计划项目(2019-3-004)

Minimally invasive reoperation for anastomotic leakage after minimally invasive resection of rectal cancer: research progress

Chenyang Ge1, Jinlin Du1,()   

  1. 1. Department of Colorectal Surgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua 321000, China
  • Received:2021-01-13 Published:2021-04-25
  • Corresponding author: Jinlin Du
引用本文:

葛琛阳, 杜金林. 直肠癌微创手术后吻合口漏的微创再手术研究进展[J]. 中华结直肠疾病电子杂志, 2021, 10(02): 113-116.

Chenyang Ge, Jinlin Du. Minimally invasive reoperation for anastomotic leakage after minimally invasive resection of rectal cancer: research progress[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2021, 10(02): 113-116.

近二十年来微创手术方式逐步成为治疗直肠癌的标准术式,但是与开腹手术方式相比,仍未能降低直肠癌术后发生吻合口漏的风险。吻合口漏仍是直肠癌术后主要的并发症之一,影响着患者的肿瘤学预后和生活质量,也是腹腔镜结直肠外科医师需要面临的挑战。对于需要手术干预的吻合口漏,选择传统的开腹再手术的处理方式,还是选择微创再手术的处理方式一直是结直肠外科医师关注的热点。本文旨在阐述直肠癌微创术后发生吻合口漏的微创手术再处理的现状和进展,讨论其可行性和安全性,以期为临床实践提供借鉴。

Although minimally invasive surgery has almost become the standard surgical approach for rectal cancer, it still fails to reduce the risk of anastomotic leakage after operation compared with open approaches. Anastomotic leakage is still one of the main complications after rectal surgery, which influences the oncological outcome and life quality of patients. Anastomotic leakage is the challenge for colorectal surgeons. It has always been a hot topic for colorectal surgeons whether to choose the traditional open surgery or the minimally invasive way for the treatment of anastomotic leakage that requires surgical intervention. This article aimed to describe the current status and progress of minimally invasive surgery for anastomotic leakage after minimally invasive rectal cancer surgery, and to discuss its feasibility and safety, hoping to provide reference for future clinical practices and clinical researches.

1
Vennix S PL, Bouvy N, Beets GL. Laparoscopic versus open total mesorectal excision for rectal cancer[J]. Cochrane Database Syst Rev, 2014, 15(4): CD005200.
2
中华医学会外科学分会结直肠外科学组. 中国直肠癌手术吻合口漏诊断、预防及处理专家共识(2019版)[J]. 中华胃肠外科杂志, 2019, 22(3): 201-206.
3
Rahbari NN, Weitz J, Hohenberger W, et al. Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer[J]. Surgery, 2010, 147(3): 339-351.
4
Gadan S, Floodeen H, Lindgren R, et al. What is the risk of permanent stoma beyond 5 years after low anterior resection for rectal cancer? A 15-year follow-up of a randomized trial[J]. Colorectal Dis, 2020 Sep 15.
5
Foppa C, Ng SC, Montorsi M, et al. Anastomotic leak in colorectal cancer patients: New insights and perspectives[J]. Eur J Surg Oncol, 2020, 46(6): 943-954.
6
Marks E, Naudin C, Nolan G, et al. Regulation of IL-12p40 by HIF controls Th1/Th17 responses to prevent mucosal inflammation[J]. Mucosal Immunol, 2017, 10(5): 1224-1236.
7
Haddad NN, Bruns BR, Enniss TM, et al. Perioperative use of nonsteroidal anti-inflammatory drugs and the risk of anastomotic failure in emergency general surgery[J]. J Trauma Acute Care Surg, 2017, 83(4): 657-661.
8
Jacobson RA, Williamson AJ, Wienholts K, et al. Prevention of anastomotic leak via local application of tranexamic acid to target bacterial-mediated plasminogen activation: A practical solution to a complex problem[J]. Ann Surg, 2019.
9
Chewning JH, Weaver CT. Development and survival of Th17 cells within the intestines: the influence of microbiome- and diet-derived signals[J]. J Immunol, 2014, 193(10): 4769-4777.
10
Marijnen CA, Kapiteijn E, van de Velde CJ, et al. Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: report of a multicenter randomized trial[J]. J Clin Oncol. 2002, 20(3): 817-825.
11
McDermott FD, Heeney A, Kelly ME, et al. Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks[J]. Br J Surg, 2015, 102(5): 462-479.
12
Boyce SA, Harris C, Stevenson A, et al. Management of low colorectal anastomotic leakage in the laparoscopic era: More than a decade of experience[J]. Dis Colon Rectum, 2017, 60(8): 807-814.
13
Zhao WT, Li NN, He D, et al. transanal tube for the prevention of anastomotic leakage after rectal cancer surgery: A systematic review and meta-analysis[J]. World J Surg, 2017, 41(1): 267-276.
14
BBeck DE, Wexner SD, Hull TL, et al. The ASCRS manual of colon and rectal surgery[M]. New York: NY: Springer, 2014.
15
Lee CM, Huh JW, Yun SH, et al. Laparoscopic versus open reintervention for anastomotic leakage following minimally invasive colorectal surgery[J]. Surg Endosc, 2015, 29(4): 931-936.
16
Eriksen JR, Ovesen H, Gogenur I. Short- and long-term outcomes after colorectal anastomotic leakage is affected by surgical approach at reoperation[J]. Int J Colorectal Dis, 2018, 33(8): 1097-1105.
17
Su H, Wu H, Bao M, et al. Indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancer[J]. BMC Surg, 2020, 20(1): 102.
18
Maeda K, Nagahara H, Shibutani M, et al. Efficacy of intracorporeal reinforcing sutures for anastomotic leakage after laparoscopic surgery for rectal cancer[J]. Surg Endosc, 2015, 29(12): 3535-3542.
19
Vallicelli C, Pirrera B, Alagna V, et al. Intraoperative endoscopy with immediate suture reinforcement of the defect in colorectal anastomosis: a pilot study[J]. Updates Surg, 2020, 72(4): 999-1004.
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