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中华结直肠疾病电子杂志 ›› 2020, Vol. 09 ›› Issue (05) : 498 -501. doi: 10.3877/cma.j.issn.2095-3224.2020.05.011

所属专题: 文献

综述

结直肠癌卵巢转移的研究现状及进展
陈怡1, 张颖1, 王颖1,()   
  1. 1. 110000 沈阳,中国医科大学附属盛京医院肿瘤科
  • 收稿日期:2020-03-20 出版日期:2020-10-25
  • 通信作者: 王颖
  • 基金资助:
    沈阳市科学技术项目(No. F13-316-1-69)

Research status and progression of ovarian metastasis from colorectal cancer

Yi Chen1, Ying Zhang1, Ying Wang1,()   

  1. 1. Medical Oncology, Shengjing Hospital Affiliated to China Medical University, Shenyang 110000, China
  • Received:2020-03-20 Published:2020-10-25
  • Corresponding author: Ying Wang
  • About author:
    Corresponding author: Wang Ying, Email:
引用本文:

陈怡, 张颖, 王颖. 结直肠癌卵巢转移的研究现状及进展[J]. 中华结直肠疾病电子杂志, 2020, 09(05): 498-501.

Yi Chen, Ying Zhang, Ying Wang. Research status and progression of ovarian metastasis from colorectal cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2020, 09(05): 498-501.

结直肠癌是当今最常见的恶性肿瘤之一,其发病率和死亡率居高不下。随着医疗水平的不断提升,结直肠癌患者的生存期显著延长,发生转移的患者也逐渐增多。卵巢转移是结直肠癌患者严重的晚期并发症,一旦发生卵巢转移,患者的生存期明显缩短,国内外对于结直肠癌卵巢转移方面的研究数据较少,但对于结直肠癌卵巢转移的相关问题逐渐被重视,文章对结直肠癌卵巢转移的流行病学、转移途径、临床特征及表现、诊疗现状以及高危因素的最新进展进行概述。

Colorectal cancer is one of the most common malignant tumors today, and its morbidity and mortality remain high. With the continuous improvement of medical level, the survival of colorectal cancer patients has significantly prolonged, and patients with metastasis have gradually increased. Ovarian metastasis is a serious late complication in patients with colorectal cancer, once ovarian metastasis occurs, the survival of the patient is significantly shortened. There were few research datas on ovarian metastasis of colorectal cancer at home and abroad, but the problems related to ovarian metastasis of colorectal cancer are gradually attracting attention. This article summarized the latest progress of epidemiology, metastatic pathways, clinical features and manifestations, current status of diagnosis and treatment, high risk factors of ovarian metastases from colorectal cancer.

表1 Bruls等[9]统计的2 312例卵巢转移性肿瘤的原发灶分布情况
表2 结直肠癌卵巢转移的临床病理特征
[1]
Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J]. CA: A Cancer Journal for Clinicians, 2018, 68(6): 394-424.
[2]
Si Y, Lee JI, Kim SH, et al. Clinicopathological characteristics of ovarian metastasis from colorectal cancer [J]. Journal of the Korean Surgical Society, 2010, 79(4): 287.
[3]
Al-Busaidi IS, Bailey T, Dobbs B, et al. Complete resection of colorectal cancer with ovarian metastases combined with chemotherapy is associated with improved survival [J]. ANZ Journal of Surgery, 2019, 89(9): 1091-1096.
[4]
Sekine K, Hamaguchi T, Shoji H, et al. Retrospective analyses of systemic chemotherapy and cytoreductive surgery for patients with ovarian metastases from colorectal cancer:a single-center experience [J]. Oncology, 2018, 95(4): 1-9.
[5]
Bignell MB, Mehta AM, Alves S, et al. Impact of ovarian metastases on survival in patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal malignancy originating from appendiceal and colorectal cancer [J]. Colorectal Disease, 2018, 20(8): 704-710.
[6]
Shimazaki J, Tabuchi T, Nishida K, et al. Synchronous ovarian metastasis from colorectal cancer: A report of two cases [J]. Oncology Letters, 2016, 12(1): 257-261.
[7]
施晓华,钱小泉,林晓华,等. 卵巢转移癌272例临床病理分析[J]. 现代妇产科进展, 2014, 23(6): 478-479.
[8]
谭景浪,韦海明. 卵巢转移性肿瘤37例临床与病理分析[J]. 中国临床新医学, 2012, 5(7): 610-613.
[9]
Bruls J, Simons M, Overbeek LI, et al. A national population-based study provides insight in the origin of malignancies metastatic to the ovary [J]. Virchows Archiv, 2015, 467(1): 79-86.
[10]
中国医师协会结直肠肿瘤专业委员会. 中国结直肠癌卵巢转移诊疗专家共识(2020版) [J/CD]. 中华结直肠疾病电子杂志, 2020, 9(2): 115-121.
[11]
Tan KL, Tan WS, Lim JF, et al. Krukenberg tumors of colorectal origin: a dismal outcome—experience of a tertiary center [J]. Inter J Colorect Dis, 2009, 25(2): 233-238.
[12]
Kim DD, Park IJ, Kim HC, et al. Ovarian metastases from colorectal cancer:a clinicopathological analysis of 103 patients [J]. Colorectal Disease, 2009, 11(1): 32-38.
[13]
赵晓明. 大肠癌卵巢转移68例临床分析[J]. 现代肿瘤医学, 2009, 17(1): 82-85.
[14]
宋望,郑洪涂,徐烨. 结肠直肠癌卵巢转移的研究进展[J]. 外科理论与实践, 2017, 22(3): 261-264.
[15]
郭春红,成科,唐源,等. 结直肠癌卵巢转移组织中CDX-2与CK7和CK20的表达及其临床意义[J]. 肿瘤预防与治疗, 2016, 29(6): 310-314.
[16]
卞巍,姚远,张海金,等. CT在诊断卵巢转移性肿瘤病理类型和转移灶来源中的应用价值[J]. 浙江大学学报(医学版), 2017, 46(5): 546-551.
[17]
Yamanishi Y, Koshiyama M, Ohnaka M, et al. Pathways of metastases from primary organs to the ovaries [J]. Obstet Gynecol Int, 2011, 2011: 612817.
[18]
陈志良,应晓江,叶平江,等. 直肠癌卵巢转移31例临床分析[J]. 浙江医学, 2014, 36(20): 1718-1719.
[19]
李桂林. 结直肠癌卵巢转移的外科治疗[J]. 医学信息(上旬刊), 2010, 23(12): 4835.
[20]
Kubeček O, Laco J, Špaček J, et al. The pathogenesis, diagnosis, and management of metastatic tumors to the ovary: a comprehensive review [J]. Clinical & Experimental Metastasis, 2017, 34(5): 295-307.
[21]
李海明,强金伟,赵书会,等. 磁共振成像诊断卵巢转移瘤的价值[J]. 中国临床医学影像杂志, 2014, 25(8): 574-578.
[22]
Guzel AB, Gulec UK, Paydas S, et al. Preoperative evaluation, clinical characteristics, and prognostic factors of nongenital metastatic ovarian tumors: review of 48 patients [J]. Eur J Gynaecol Oncol, 2012, 33(5): 493-497.
[23]
马凤华,强金伟. 磁共振成像在转移性卵巢肿瘤的应用现状[J].中国医学计算机成像杂志, 2015, 21(2): 190-192.
[24]
Doğanay M, Topcu HO, Kokanali MK, et al. Krukenberg carcinoma metastasized from stomach resembling mucinous cystadenocarcinoma of the ovary [J]. J Exper Thera Oncol, 2015, 11(1): 23-26.
[25]
Kir G, Gurbuz A, Karateke A, et al. Clinicopathologic and immunohistochemical profile of ovarian metastases from colorectal carcinoma [J]. World J Gastroint Surg, 2010, 2(4): 109-116.
[26]
王敏,朴金松,高蔚樱,等. 56例消化道来源卵巢转移性肿瘤的临床病理特征[J].中国医药指南, 2014, (12): 2-4, 6.
[27]
宋英慧. 转移性卵巢肿瘤44例临床分析[D]. 吉林: 延边大学, 2013.
[28]
周立民. 手术和保守治疗结直肠癌卵巢转移效果对比[J]. 四川医学, 2012, 33(6): 1048-1050.
[29]
Cutait R, Lesser ML, Enker WE. Prophylactic oophorectomy in surgery for large-bowel cancer [J]. Diseases of the Colon & Rectum, 1983, 26(1): 6-11.
[30]
Ganesh K, Shah RH, Vakiani E, et al. Clinical and genetic determinants of ovarian metastases from colorectal cancer [J]. Cancer, 2017, 123(7): 1134-1143.
[31]
马骏,余敏华,王诚洁,等. 结直肠癌术后卵巢转移18例临床分析[J].中国妇产科临床杂志, 2014, 15(5): 439-441.
[32]
Goéré D, Davean C, Elias D, et al. The differential response to chemotherapy of ovarian metastases from colorectal carcinoma [J]. Eur J Surg Oncol, 2008, 34(12): 1335-1339.
[33]
孙建华,姬忠贺,于洋,等.细胞减灭术加腹腔热灌注化疗治疗卵巢癌腹膜转移癌的临床研究[J]. 肿瘤防治研究, 2016, 43(4): 282-286.
[34]
Kuijpers AMJ, Mehta AM, Aalbers AGJ, et al. Treatment of ovarian metastases of colorectal and appendiceal carcinoma in the era of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy [J]. European Journal of Surgical Oncology (EJSO), 2014, 40(8): 937-942.
[35]
Bakkers C, Meer RVD, Roumen RM, et al. Incidence, risk factors, treatment, and survival of ovarian metastases of colorectal origin: a Dutch population-based study [J]. Inter J Colorect Dis, 2020, 35(3): 1035-1044.
[36]
李继林. 结直肠癌卵巢转移灶HER2和EGFR表达的检测与分析[D]. 广西: 广西医科大学, 2019.
[37]
Kavanagh DO, Chambers G, O'Grady L, et al. Is overexpression of HER-2 a predictor of prognosis in colorectal cancer [J]. BMC Cancer, 2009, 9: 1-3.
[38]
蔡艺斌. 结直肠癌卵巢转移高危因素分析[D]. 福建: 福建医科大学, 2016.
[39]
黄深,张森,高枫,等. 380例结直肠癌卵巢转移的相关因素分析[J]. 中国肿瘤临床, 2011, 38(2): 89-93.
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