研究普芦卡必利用于老年结肠镜前肠道准备的效果及干预时长。

选取中国医科大学附属第四医院90例老年结肠镜前肠道准备患者为研究对象，随机分为三组，A组单纯给予聚乙二醇电解质散溶液，结肠镜检查前4 h给予，B、C组另加用普芦卡必利，分别在结肠镜检前1 d、3 d使用，比较三组清洁效果、肠道内气泡情况及息肉检出率。

B、C组横——降结肠、直肠——乙状结肠、升结肠——回盲部清洁评分均显著高于A组（P<0.05），B、C两组在上述部位清洁评分比较差异无统计学意义（P>0.05）；B、C气泡显著少于A组（Χ²值分别为5.455，4.022，P均<0.05），B、C两组组间比较差异无统计学意义（P>0.05）；三组>10 mm和三组≤10 mm息肉检出率比较差异无统计学意义（Χ²值分别为0.207，0.274，P均>0.05）。

普芦卡必利联合聚乙二醇电解质散溶液用于结肠镜前肠道准备效果显著，可改善清肠效果，降低肠道内气泡情况，可作为老年结肠镜前检查的有效方式。

To study the effect and the length of intervention on the bowel preparation before colonoscopy in the elderly.

We selected 90 elderly patients with intestinal tract preparation before colonoscopy, and divided into three groups, group A was treated with polyethylene glycol electrolyte solution only 4 h before colonoscopy, Group B and group C were treated with prucalopride and polyethylene glycol electrolyte solution 1 d and 3 d before colonoscopy respectively, the cleaning effect, intestinal bubble status and polyp detection rate were compared between the three groups.

Descending colon, sigmoid colon, ascending colon and rectum-ileocecus clean scores of B and C groups were significantly higher than that of group A (P<0.05), there was no significant difference between the two groups of B and C (P>0.05). The bubbles of group B and C were significantly less than that of group A (P>0.05), there was no significant difference between the two groups of B and C (P<0.05), in the three group, the polyp detection rate had no significant difference (Χ²=0.207, Χ²=0.274, all P>0.05).

Prucalopride combined with polyethylene glycol electrolyte solution for the bowel preparation is effective, which can improve the clearing effect, reduction of intestinal air bubbles, can be used as an effective method for colonoscopy examination in elderly patients.