| [1] | Abraham C, Medzhitov R. Interactions between the host innate immune system and microbes in inflammatory bowel disease [J]. Gastroenterology, 2011, 140(6):1729-1737. | 
																													
																						| [2] | Kaser A, Zeissig S, Blumberg R. Inflammatory bowel disease [J]. Annu Rev Immunol, 2010, 28(1):573-621. | 
																													
																						| [3] | Guarnieri DJ, Dileone RJ.MicmRNAs:a new class of gene regulators [J]. Ann Med, 2008, 40(3):197-208. | 
																													
																						| [4] | Pekow JR, Kwon JH. MicroRNAs in inflammatory bowel disease [J]. Inflamm Bowel Dis, 2012, 18(1):187-193. | 
																													
																						| [5] | Polytarchou C, Oikonomopoulos A, Mahurkar S, et al. Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology [J]. Inflamm Bowel Dis, 2015, 21(11):2533-2539. | 
																													
																						| [6] | Felwick R., Dingley G., Sanchez-Elsner T., et al. MicroRNA23a is overexpressed in the colonic epithelium in Crohn′s disease [J]. Journal of Crohn′s and Colitis , 2016, 150(4):S375-S375. | 
																													
																						| [7] | Yu Q, Zhang S, Chao K, et al. E3 Ubiquitin ligase RNF183 Is a Novel Regulator in Inflammatory Bowel Disease [J]. J Crohns Colitis, 2016, 10(6):713-725. | 
																													
																						| [8] | Wu W, He C, Liu C, et al. miR-10a inhibits dendritic cell activation and Th1/Th17 cell immune responses in IBD [J]. Gut, 2015, 64(11):1755-1764. | 
																													
																						| [9] | Takagi T, Naito Y, Mizushima K, et al. Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis [J]. J Gastroenterol Hepatol, 2010, 25(1):S129-S133. | 
																													
																						| [10] | Heinsbroek SE, Squadrito ML, Schilderink R, et al. miR-511-3p, embedded in the macrophage mannose receptor gene, contributes to intestinal inflammation [J]. Mucosal Immunol, 2016, 9(4):960-973. | 
																													
																						| [11] | Zhang L, Shen J, Cheng J, et al. MicroRNA-21 regulates intestinal epithelial tight junction permeability [J]. Cell Biochem Funct, 2015, 33(4):235-240. | 
																													
																						| [12] | Yang Y, Ma Y, Shi C, et al. Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase RhoB [J]. Biochem Biophys Res Commun, 2013, 434(4):746-752. | 
																													
																						| [13] | Ye D, Guo S, Al-Sadi R, et al. MicroRNA regulation of intestinal epithelial tight junction permeability [J]. Gastroenterology, 2011, 141(4):1323-1333. | 
																													
																						| [14] | Chen Y, Wang C, Liu Y, et al. miR-122 targets NOD2 to decrease intestinal epithelial cell injury in Crohn′s disease [J]. Biochem Biophys Res Commun, 2013, 438(1):133-139. | 
																													
																						| [15] | Schaefer JS, Attumi T, Opekun AR, et al. MicroRNA signatures differentiate Crohn′s disease from ulcerative colitis [J]. BMC Immunol, 2015, 16(1):5. | 
																													
																						| [16] | Krissansen GW, Yang Y, Mcqueen FM, et al. Overexpression of miR-595 and miR-1246 in the sera of patients with active forms of inflammatory bowel disease [J]. Inflamm Bowel Dis, 2015, 21(3):520-530. | 
																													
																						| [17] | Yu N, Zhang YP, Wang FY. Differential expression of miR-155 as a novel fecal-based diagnostic marker for inflammatory bowel disease [J]. J Dig Dis, 2014, 15, SUPPL. (1):156. | 
																													
																						| [18] | Yi F, Zhou R, Xun J, et al. The utility of fecal microRNAs and S100A12 in the diagnosis of inflammatory bowel disease [J]. J Gastroenterol Hepatol, 2013, 28 SUPPL. (3):146. | 
																													
																						| [19] | Iborra M, Bernuzzi F, Correale C, et al. Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease [J]. Clin Exp Immunol, 2013, 173(2):250-258. | 
																													
																						| [20] | Wang H, Zhang S, Yu Q, et al. Circulating MicroRNA223 is a New Biomarker for Inflammatory Bowel Disease [J]. Medicine(Baltimore), 2016, 95(5):e2703. | 
																													
																						| [21] | Link A, Schoenauen K, Le N, et al. Differential expression of micrornas in sera and feces of patients with inflammatory bowel disease [J]. United Eur Gastroenterol J, 2015, 3(5):A236-A237. | 
																													
																						| [22] | Pott F, Cichon C, Brückner M, et al. MicroRNA-320 as a biomarker to monitor the course of disease activity in experimental colitis as well as in patients with inflammatory bowel disease [J]. United Eur Gastroenterol J, 2(1):A214. | 
																													
																						| [23] | Ibrahim AF, Weirauch U, Thomas M, et al. MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma [J]. Cancer Res, 2011, 71(15):5214-5224. | 
																													
																						| [24] | Lanford RE, Hildebrandt-Eriksen ES, Petri A, et al. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection [J]. Science, 2010, 327(5962):198-201. | 
																													
																						| [25] | Wu F, Zikusoka M, Trindade A, et al. MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha [J]. Gastroenterology, 2008, 135(5):1624-1635. | 
																													
																						| [26] | Simonson B, Das S. MicroRNA Therapeutics: the Next Magic Bullet? [J]. Mini Rev Med Chem, 2015, 15(6):467-474. | 
																													
																						| [27] | Viscido A, Bagnardi V, Sturniolo GC, et al. Survival and causes of death in Italian patients with ulcerative colitis. A GISC nationwide study [J]. Dig Liver Dis, 2001, 33(8):686-692. | 
																													
																						| [28] | Feagins L A, Souza R F, Spechler S J. Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer [J]. Nat Rev Gastroenterol Hepatol, 2009, 6(5):297-305. | 
																													
																						| [29] | Ludwig K, Fassan M, Mescoli C, et al. PDCD4/miR-21 dysregulation in inflammatory bowel disease-associated carcinogenesis [J]. Virchows Arch, 2013, 462(1):57-63. | 
																													
																						| [30] | Ranjha R, Aggarwal S, Bopanna S, et al. Site-Specific MicroRNA Expression May Lead to Different Subtypes in Ulcerative Colitis [J]. PLoS One, 2015, 10(11):e142869. | 
																													
																						| [31] | Olaru AV, Selaru FM, Mori Y, et al. Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation [J]. Inflamm Bowel Dis, 2011, 17(1):221-231. | 
																													
																						| [32] | Olaru AV, Yamanaka S, Vazquez C, et al. MicroRNA-224 negatively regulates p21 expression during late neoplastic progression in inflammatory bowel disease [J]. Inflamm Bowel Dis, 2013, 19(3):471-480. | 
																													
																						| [33] | Kunte D, Savkovic S, Qi W, et al. MiR-34a as potential fecal biomarker Colitis-induced Colorectal cancer [J]. Inflammatory Bowel Dis, 2011, 17: S86-S87. |