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中华结直肠疾病电子杂志 ›› 2016, Vol. 05 ›› Issue (06) : 528 -532. doi: 10.3877/cma.j.issn.2095-3224.2016.06.015

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经验交流

改良结肠运输试验在慢性便秘鉴别诊断及治疗中的价值
汤东1, 黄玉琴2, 王杰2, 蒋学通1, 徐传奇1, 高俊1, 王伟1, 王道荣1,(), 李宁3,()   
  1. 1. 225001 江苏,扬州大学临床医学院(江苏省苏北人民医院)普外科,普通外科研究所
    2. 116044 辽宁,大连医科大学普外科
    3. 210002 江苏,南京大学医学院临床学院(南京军区南京总医院全军)普通外科研究所
  • 收稿日期:2016-05-10 出版日期:2016-12-25
  • 通信作者: 王道荣, 李宁
  • 基金资助:
    中国博士后科学基金资助项目(No.2013M530243)

The differential value of modified colonic transit test in the diagnosis and treatment of chronic constipation

Dong Tang1, Yuqin Hang2, Jie Wang2, Xuetong Jiang1, Chuanqi Xu1, Jun Gao1, Wei Wang1, Daorong Wang1,(), Ning Li3,()   

  1. 1. Department of General Surgery, Institute of General Surgery, Clinical Medical College, Yangzhou University (Subei People′s Hospital of Jiangsu Province), Yangzhou 225001, China
    2. Department of General Surgery, Dalian Medical University, Dalian 116044, China
    3. Research Institute of General Surgery, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China
  • Received:2016-05-10 Published:2016-12-25
  • Corresponding author: Daorong Wang, Ning Li
  • About author:
    Corresponding author: Wang Daorong, Email:
    Li Ning, Email:
引用本文:

汤东, 黄玉琴, 王杰, 蒋学通, 徐传奇, 高俊, 王伟, 王道荣, 李宁. 改良结肠运输试验在慢性便秘鉴别诊断及治疗中的价值[J]. 中华结直肠疾病电子杂志, 2016, 05(06): 528-532.

Dong Tang, Yuqin Hang, Jie Wang, Xuetong Jiang, Chuanqi Xu, Jun Gao, Wei Wang, Daorong Wang, Ning Li. The differential value of modified colonic transit test in the diagnosis and treatment of chronic constipation[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 05(06): 528-532.

目的

探讨改良结肠运输试验对慢性便秘鉴别诊断及指导治疗中的价值。

方法

选取2013年1月至2015年6月,江苏省苏北人民医院胃肠外科便秘专科门诊诊治的慢性便秘患者52例,对52例不同程度排便困难患者和10例健康对照者进行改良结肠运输试验,即在禁食促排便药物72 h后行上消化道钡餐检查,6 h和72 h后再分别拍摄腹部平片,观察钡剂在肠道残留情况,根据检查结果分类并予以相关治疗。

结果

所有患者未见胃肠道器质性病变。7 h后,10例健康对照者肠道内无钡剂残留,39例患者钡剂残留在结肠(诊断为慢传输型),5例患者钡剂残留在直肠(诊断为出口梗阻型),而8例患者钡剂残留在结直肠内(诊断为混合型)。所有患者予以促结肠动力药物普芦卡必利(2 mg/d)±乳果糖(30 mg/d)治疗,其中1例慢传输型患者、1例出口梗阻型患者和8例混合型患者无效,予以施行腹腔镜下金陵术治愈。

结论

改良结肠运输试验对慢性便秘的诊断具有重要价值,有助于不同便秘类型的鉴别及针对性治疗。

Objective

To explore the value of modified colonic transit test in differential diagnosis and treatment of chronic constipation.

Methods

52 patients with chronic constipation at Subei People′s Hospital were choosen between January 2013 and June 2015. Modified colonic transit test was performed in 52 patients with different degrees of discharge difficulty and 10 healthy controls. The procedure of modified colonic transit test was as follows: after 72 hours of abstaining from all the laxatives, the patients were performed upper gastrointestinal barium meal examination, and the plain abdominal radiograph were taken 6 hours and 72 hours later respectively, which were used to observe the residues of barium in the colon and rectum, and then the related treatments were performed.

Results

All patients had no gastrointestinal lesions. After 72 hours, 10 healthy controls had no barium residue, and 39 patients had barium residue in colon (diagnosed as a slow transmission type of constipation), and 5 patients had barium residue in the rectum (diagnosis as an outlet obstruction type of constipation), and 8 patients had barium residue in colon and rectum (diagnosis as a mixed type of constipation). All patients were treated with prucalopride (2 mg/d) with or without lactulose (30 mg/d), in which 1 patients with slow transmission type, and 1 patients with outlet obstruction and 8 patients with mixed type of constipation were ineffective and were cured by laparoscopic Jinling procedure.

Conclusions

Modified colonic transit test was useful for the diagnostic of chronic constipation, which is helpful for the differential diagnosis and treatment of different types of constipation.

图1 改良结肠传输试验:钡餐后72 h无排便并且按照钡剂在结肠内存留和分布情况,可分为慢传输型便秘(钡剂残留在结肠)、出口梗阻型(钡剂残留在直肠)和混合型便秘(钡剂残留在结直肠内),而正常健康对照组肠道内钡剂则在钡餐后72 h内完全排空
图2 改良结肠传输试验显示的结肠形态影像学:2A结肠形态正常,结肠走向正常,无扭曲;2B横结肠冗长:横结肠总长>35 cm,部分下垂于盆腔;2C结肠张力偏低:肝脾曲位置均偏低,大部分结肠位于盆腔;2D脾曲综合征:横结肠过长、下垂及脾部积气
表1 改良结肠传输试验及指导性治疗结果表[例(%)]
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