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中华结直肠疾病电子杂志

中华结直肠疾病电子杂志 ›› 2016, Vol. 05 ›› Issue (03) : 198 -203. doi: 10.3877/cma.j.issn.2095-3224.2016.03.001

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重视直肠癌低位前切除综合征的预防与治疗
秦启元1, 黄斌杰1, 王磊1,†()   
  1. 1. 510655　广州，中山大学附属第六医院结直肠肛门外科
  • 收稿日期:2016-04-21 出版日期:2016-06-25
  • 通信作者: 王磊
  • 基金资助:
    国家自然科学基金资助项目(No.81573078)

Low anterior resection syndrome: current awareness, prevention, and treatment

Qiyuan Qin1, Binjie Huang1, Lei Wang1,†()   

  1. 1. Department of Colorectal Surgery, Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China
  • Received:2016-04-21 Published:2016-06-25
  • Corresponding author: Lei Wang
  • About author:
    Corresponding author: Wang Lei, Email:
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引用本文：

秦启元, 黄斌杰, 王磊. 重视直肠癌低位前切除综合征的预防与治疗[J]. 中华结直肠疾病电子杂志, 2016, 05(03): 198-203.

Qiyuan Qin, Binjie Huang, Lei Wang. Low anterior resection syndrome: current awareness, prevention, and treatment[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 05(03): 198-203.

直肠癌诊疗技术的发展延长了患者的生存时间，各种保肛手术的广泛应用减少了永久性造口的比例，这使得患者术后的肠道功能与生活质量成为新的热点问题。在直肠癌低位前切除术后，25%~90%的患者会出现不同程度的肠道功能异常，表现为便急、便频、排空障碍和大便失禁等，这一系列症候群被称之为低位前切除综合征。严重的低位前切除综合征显著影响患者的生活质量。然而该疾病目前在国内尚未得到足够的认识，亦未建立起规范的防治体系或诊治指南。本文就低位前切除综合征的理论基础、诊断要点和防治措施进行梳理，以期为直肠癌术后肠道功能的改善与研究提供借鉴。

关键词: 直肠肿瘤, 外科手术, 治疗, 生活质量

Advances in the management of rectal cancer have contributed to an improved survival and increasing use of sphincter-preserving resection in the last decades, which makes the issue of postoperative bowel dysfunction and quality of life draw more concerns. It is estimated that 25%~90% of the patients undergoing low anterior resection for rectal cancer will experience postoperatively a constellation of symptoms including fecal urgency, increased stool frequency, bowel fragmentation, emptying difficulties and incontinence, collectively referred to as the low anterior resection syndrome (LARS). Severe LARS is a major problem with an immense impact on patients? quality of life. However, there is deficient awareness regarding the concept of LARS, as well as the strategy of prevention and treatment in China. In this review, we aim to summarize the pathophysiology, diagnosis and key points of prevention and treatment for LARS, providing guidance for clinical practice and future study.

Key words: Rectal neoplasms, Surgical procedures, operative, Treatment, Quality of life
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