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中华结直肠疾病电子杂志 ›› 2015, Vol. 04 ›› Issue (04) : 385 -391. doi: 10.3877/cma.j.issn.2095-3224.2015.04.08

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胃肠胰神经内分泌肿瘤的临床诊治
朱利明1,(), 钟海均1   
  1. 1. 310022 杭州,浙江省肿瘤医院胃肠肿瘤内科
  • 收稿日期:2015-05-12 出版日期:2015-08-25
  • 通信作者: 朱利明

Clinical diagnosis and treatment of gastrointestinal pancreatic neuroendocrine tumor

Li-ming ZHU1,(), Hai-jun ZHONG1   

  1. 1. Department of Gastrointestinal oncology, Zhejiang cancer hospital, Hangzhou 310012, China
  • Received:2015-05-12 Published:2015-08-25
  • Corresponding author: Li-ming ZHU
  • About author:
    Corresponding author: ZHU Li-ming, Email:
引用本文:

朱利明, 钟海均. 胃肠胰神经内分泌肿瘤的临床诊治[J]. 中华结直肠疾病电子杂志, 2015, 04(04): 385-391.

Li-ming ZHU, Hai-jun ZHONG. Clinical diagnosis and treatment of gastrointestinal pancreatic neuroendocrine tumor[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2015, 04(04): 385-391.

胃肠胰神经内分泌肿瘤是起源于神经内分泌组织的一组异质性肿瘤,近年来生长抑素类似物已经应用于神经内分泌肿瘤的临床治疗,新药物如血管靶向治疗及mTOR通路阻滞药物等也为神经内分泌肿瘤的治疗带来新的曙光。

Gastroenteropancreatic neuroendocrine tumors(GEP-NETs)are a heterogeneous group of neoplasms arising from the diffuse neuroendocrine system.Somatostatin analogs, initially developed for control of hormonal syndromes, have recently been used to inhibit tumor growth.The advent of new therapies such as newer drugs, targeting angiogenesis and mammalian target of rapamycin(mTOR)pathway for PNETs and carcinoid tumors have introduced a paradigm shift in the management of this heterogeneous malignancy.

表1 胃肠胰神经内分泌肿瘤的分级标准表(WHO,2010)
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