Abstract:

Colorectal cancer is the third most common malignant tumor worldwide. Early diagnosis can significantly improve patient prognosis and survival rates, but current screening and diagnostic methods have limitations, necessitating the search for new alternatives. Exosomes, as key mediators of intercellular communication and information carriers, play a crucial role in tumor development and progression and can serve as potential sources of diagnostic biomarkers. In recent years, circulating exosome-related biomarkers have been extensively studied. This non-invasive detection method analyzes exosome-related contents derived from tumor cells in peripheral circulation, such as nucleic acids, proteins, lipids, and metabolites, to comprehensively reflect information about the primary tumor. It enables simple, precise, and real-time monitoring of tumor progression, showing promise for clinical application and providing new insights for the early screening and accurate diagnosis of colorectal cancer.

Key words: Colorectal neoplasms, Exosomes, Biomarkers, Diagnosis