The number of colorectal cancer patients is increasing year by year and the proportion of patients with locally advanced cancer was higher in China. The Pelvic tissue can be invaded by tumor, especially in the cases with upper rectal cancer or sigmoid cancer. The bladder is the most commonly invaded tissue. There are some controversies about surgical treatment for locally advanced rectal cancer. In this video, laparoscopic expanded radical resection for rectal cancer with bladder invasion was shown, and partial cystectomy also has been performed in this case. Postoperatively, six cycles of adjuvant chemotherapy (Xelox) was performed for the patient, and no obvious recurrence was observed during one year follow-up. The appropriate treatment plan should be formulated according to the state of the tumor, especially in the cases with locally advanced rectal cancer with bladder invasion with the purpose of increasing the chance of R0 resection.