To explore the clinical effects of oral nutrition supplementation on patients with laparoscopic colorectal cancer during perioperative period.

Follow the random number table method, patients with laparoscopic colorectal cancer surgical treatment from Xuzhou Central Hospital from July 2018 to July 2019 were divided into 50 cases of oral nutrition supplements (ONS group) and 50 cases of routine group, and the perioperative clinical indicators of the two groups were compared. The general data of patients, the levels of albumin and prealbumin of the perioperative period, and the complications etc during the perioperative period were analyzed.

Nighty-three cases completed clinical trials, including 43 cases of ONS group, fifty cases of normal group. Albumin (t=3.2948, P=0.0014)and prealbumin levels (t=3.5386, P=0.0006) of ONS group were higher than that of normal group on the seventh day after surgery, difference was statistically significant. The time of the first exhaust and defecation between the ONS group and the routine group [(49.2±10.3) h vs. (60.5±13.1) h, t=-4.5696; P<0.001] was statistically significant. Perioperative complications of two groups such as pulmonary infection, infection of incision, anastomotic leakage had no significant statistically differences. The tolerance rate of enteral nutrition of ONS group was 90.0% (45/50).

Oral nutrition supplementation on patients with laparoscopic colorectal cancer during perioperative period is safe and effective, which can improve the nutritional status of patients and promote the recovery of digestive tract function.