With the continuous advancement of minimally invasive surgical concepts and techniques, natural orifice specimen extraction surgery (NOSES) has demonstrated advantages such as minimal trauma, rapid recovery, and excellent cosmetic outcomes in colorectal cancer surgery. However, the traditional double-stapling technique is associated with a structural defect known as the "dog-ear" deformity, which may increase the risk of anastomotic leakage. This paper reports a case of total laparoscopic double-purse-string anastomosis applied in radical resection of rectal cancer. By manually placing double purse-string sutures and avoiding the use of multiple staplers, this surgical approach not only reduces the risk of anastomotic complications but also decreases the consumption of surgical consumables. The patient had an uneventful postoperative recovery without complications, confirming the feasibility and safety of this technique in laparoscopic colorectal surgery.