Clinical effect of Nano-carbon on 253 groups of lymph node dissection in laparoscopic radical resection of rectal cancer

doi:10.3877/cma.j.issn.2095-3224.2023.06.006

Abstract

Abstract:

Objective

To assess the effect of nano-carbon in clearing the No. 253 lymph nodes during laparoscopic radical resection of rectal cancer (Dixon).

Methods

Eighty patients who underwent laparoscopic radical resection of rectal cancer (Dixon) at Shanxi Cancer Hospital from January 2021 to December 2021 were prospectively enrolled. The patients were randomly divided into an experimental group receiving nano-carbon injection and a control group, with 40 patients in each group. After surgery, specimens were sent to the pathology department, and dissections were performed on the No. 253 lymph nodes and non-No. 253 lymph nodes.

Results

Nano-carbon significantly increased the number of detected lymph nodes (t=2.161, P=0.037). The experimental group showed a significantly higher number of No. 253 lymph nodes cleared compared to the control group. However, there was no statistically significant difference in the positivity rate of No. 253 lymph nodes between the two groups (χ²=0.528, P>0.05). The experimental group also had a higher number of non-No. 253 lymph nodes cleared compared to the control group, with no statistically significant difference in the positivity rate between the two groups (χ²=0.256, P>0.05).

Conclusion

Nano-carbon can significantly increase the detection of lymph nodes after rectal cancer surgery, but it does not improve the positive detection rate of No. 253 lymph nodes.

Key words: Rectal neoplasms, Laparoscopes, Nano-carbon, Lymph node, Prognosis

Yanjun Lu, Jian Ma, Pengyu Bai, Linghong Guo, Haiyi Liu, Bo Jiang, Wenqi Bai, Yixun Zhang. Clinical effect of Nano-carbon on 253 groups of lymph node dissection in laparoscopic radical resection of rectal cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2023, 12(06): 473-477.

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References 15

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组别	例数	手术时间（min）	术中出血量（mL）	术后排气时间（天）	术后并发症（例）	术后住院天数（天）
实验组	40	138.6±18.0	39.3±18.5	3.0±0.8	6	10.7±3.5
对照组	40	150.4±19.4	35.0±17.6	2.8±0.9	7	9.8±3.4
检验值		t=2.001	t=0.744	t=0.755	χ²=0.092	t=0.773
P值		0.053	0.462	0.455	0.762	0.444

组别	例数	手术时间（min）	术中出血量（mL）	术后排气时间（天）	术后并发症（例）	术后住院天数（天）
实验组	40	138.6±18.0	39.3±18.5	3.0±0.8	6	10.7±3.5
对照组	40	150.4±19.4	35.0±17.6	2.8±0.9	7	9.8±3.4
检验值		t=2.001	t=0.744	t=0.755	χ²=0.092	t=0.773
P值		0.053	0.462	0.455	0.762	0.444

组别	例数	清扫淋巴结平均数（枚）	253组淋巴结平均数（枚）	非253组淋巴结平均数（枚）
实验组	40	17.6±3.3	1.9±1.1	15.7±3.0
对照组	40	15.4±3.8	1.3±0.9	14.1±3.6
t值		2.161	1.960	1.807
P值		0.037	0.057	0.079

组别	例数	清扫淋巴结平均数（枚）	253组淋巴结平均数（枚）	非253组淋巴结平均数（枚）
实验组	40	17.6±3.3	1.9±1.1	15.7±3.0
对照组	40	15.4±3.8	1.3±0.9	14.1±3.6
t值		2.161	1.960	1.807
P值		0.037	0.057	0.079

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